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CENP-B cooperates with Set1 in bidirectional transcriptional silencing and geno…

Lorenz(David R),Mikheyeva(Irina V),Johansen(… Mol Cell Biol 2013-01-03

Regulation of transposable elements (TEs) is critical to the integrity of the host genome. The fission yeast Schizosacch...

Computational screening and molecular dynamics simulation of disease associated…

Kumar(Ambuj),Purohit(Rituraj) Mutat Res 2013-02-26

Aneuploidy and chromosomal instability (CIN) are hallmarks of most solid tumors. Mutations in centroemere proteins have ...

Arabidopsis thaliana AUCSIA-1 regulates auxin biology and physically interacts …

Molesini(Barbara),Pandolfini(Tiziana),Pii(Yo… PLoS One 2013-02-22

Aucsia is a green plant gene family encoding 44-54 amino acids long miniproteins. The sequenced genomes of most land pla...

Mitogen-activated protein kinase (MEK/ERK) inhibition sensitizes cancer cells t…

Mayes(Patrick A),Degenhardt(Yan Y),Wood(Andr… Int J Cancer 2013-01-29

Inhibition of centromere-associated protein-E (CENP-E) has demonstrated preclinical anti-tumor activity in a number of t...

Putting CENP-A in its place.

Stellfox(Madison E),Bailey(Aaron O),Foltz(Da… Cell Mol Life Sci 2013-03-04

The centromere is the chromosomal region that directs kinetochore assembly during mitosis in order to facilitate the fai...

Anti-centromere antibodies in a large cohort of systemic sclerosis patients: co…

Mahler(Michael),You(Daniel),Baron(Murray),Ta… Clin Chim Acta 2013-07-08

Anti-centromere antibodies (ACA) are useful biomarkers in the diagnosis of systemic sclerosis (SSc) where they are found...

Live-cell imaging visualizes frequent mitotic skipping during senescence-like g…

Suzuki(Masatoshi),Yamauchi(Motohiro),Oka(Yas… Int J Radiat Oncol Biol Phys 2012-07-31

Senescence-like growth arrest in human solid carcinomas is now recognized as the major outcome of radiotherapy. This stu...

Replicating centromeric chromatin: spatial and temporal control of CENP-A assem…

Nechemia-Arbely(Yael),Fachinetti(Daniele),Cl… Exp Cell Res 2012-08-23

The centromere is the fundamental unit for insuring chromosome inheritance. This complex region has a distinct type of c...

CENP-T proteins are conserved centromere receptors of the Ndc80 complex.

Schleiffer(Alexander),Maier(Michael),Litos(G… Nat Cell Biol 2012-08-13

Centromeres direct the assembly of kinetochores, microtubule-attachment sites that allow chromosome segregation on the m...

T time for point centromeres.

Gascoigne(Karen E),Cheeseman(Iain M) Nat Cell Biol 2012-08-13

The diverse nature of eukaryotic centromere structure has led to a prevailing view that the kinetochore-chromatin interf...

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