...Rad50-Nbs1 (MRN) DNA repair complex as a double-strand break. If unabated, MRN elicits a double-strand break repair resp...
...Rad50-Nbs1 (MRN) complex, γ-H2AX and 53BP1, the ATM and ATR signal-transducing kinases and downstream effectors, includi...
...rad50, 52 and 57 strains sporulated, but the spores were inviable. The rad6 strain did not sporulate. The rad50, 52 and ...
...RAD50 in asynchronously growing cells. Among the few molecules exhibiting shift in the rad50 mutant, the residual resect...
...RAD50/NBS1. To investigate the NBS phenotype in more detail, we combined the mouse mimic of the most common patient muta...
...rad50 expression was observed among the three groups of cells. Immunohistochemistry also showed increased protein levels...
...RAD50) were significantly overexpressed. The Fanconi anemia/BRCA2 pathway, responsible for homologous recombination DNA ...
...RAD50-NBS1 (MRN) complex accumulates at sites of DNA double-strand breaks in large chromatin domains flanking the lesion...
...Rad50/Xrs2 (MRX) complex in Saccharomyces cerevisiae has well-characterized functions in DNA double-strand break process...
...RAD50 and p21) were prominently altered, and six (ATM, CCND2, CCNF, CDC20, CDK1A and RAD50) were commonly altered with b...
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