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Adenovirus core protein VII protects the viral genome from a DNA damage respons…

Karen(Kasey A),Hearing(Patrick) J Virol 2011-06-14

...Rad50-Nbs1 (MRN) DNA repair complex as a double-strand break. If unabated, MRN elicits a double-strand break repair resp...

Probing the telomere damage response.

Rai(Rekha),Chang(Sandy) Methods Mol Biol 2011-08-01

...Rad50-Nbs1 (MRN) complex, γ-H2AX and 53BP1, the ATM and ATR signal-transducing kinases and downstream effectors, includi...

The Role of Radiation (rad) Genes in Meiotic Recombination in Yeast.

Game(J C),Zamb(T J),Braun(R J),Resnick(M),Ro… Genetics 2010-06-28

...rad50, 52 and 57 strains sporulated, but the spores were inviable. The rad6 strain did not sporulate. The rad50, 52 and ...

RAD50 is required for efficient initiation of resection and recombinational rep…

Westmoreland(Jim),Ma(Wenjian),Yan(Yan),Van H… PLoS Genet 2010-01-06

...RAD50 in asynchronously growing cells. Among the few molecules exhibiting shift in the rad50 mutant, the residual resect...

NBS1 cooperates with homologous recombination to counteract chromosome breakage…

Brugmans(Linda),Verkaik(Nicole S),Kunen(Maur… DNA Repair (Amst) 2010-02-05

...RAD50/NBS1. To investigate the NBS phenotype in more detail, we combined the mouse mimic of the most common patient muta...

High expression of the circadian gene mPer2 diminishes the radiosensitivity of …

Chang(L),Liu(Y Y),Zhu(B),Li(Y),Hua(H),Wang(Y… Braz J Med Biol Res 2010-05-06

...rad50 expression was observed among the three groups of cells. Immunohistochemistry also showed increased protein levels...

Malignant pleural mesothelioma: genome-wide expression patterns reflecting gene…

Røe(Oluf Dimitri),Anderssen(Endre),Sandeck(H… Lung Cancer 2010-02-23

...RAD50) were significantly overexpressed. The Fanconi anemia/BRCA2 pathway, responsible for homologous recombination DNA ...

A divalent FHA/BRCT-binding mechanism couples the MRE11-RAD50-NBS1 complex to d…

Hari(Flurina J),Spycher(Christoph),Jungmiche… EMBO Rep 2010-07-27

...RAD50-NBS1 (MRN) complex accumulates at sites of DNA double-strand breaks in large chromatin domains flanking the lesion...

A novel function for the Mre11-Rad50-Xrs2 complex in base excision repair.

Steininger(Sylvia),Ahne(Fred),Winkler(Klaudi… Nucleic Acids Res 2010-04-22

...Rad50/Xrs2 (MRX) complex in Saccharomyces cerevisiae has well-characterized functions in DNA double-strand break process...

Profiling of cell cycle genes of breast cells exposed to etodolac.

Roy(D),Arason(G A),Chowdhury(B),Mitra(A),Cal… Oncol Rep 2010-07-13

...RAD50 and p21) were prominently altered, and six (ATM, CCND2, CCNF, CDC20, CDK1A and RAD50) were commonly altered with b...

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