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From Bench to Bedside: Ethical and Clinical Best Practices for Genome Editing...

Ortiz-Bueno(M),Zinghirino(F),Serra(PP),Pas... Int J Mol Sci 2026-02-02

...CRISPR)-based systems, of which the latter has emerged as the most accessible, versatile, and popular. While GE holds gr...

Targeted Gene Modification of HMGR Enhances Biosynthesis of Terpenoid and Phe...

Skaliter(O),Gura(A),Livneh(Y),Cohen(R),Shk... Int J Mol Sci 2026-02-04

...CRISPR/Cas9 system to genetically modify the N-terminal regulatory domain of HMGR in petunia (Petunia × hybrida) and let...

Ovarian Cancer Susceptibility and Chemosensitivity to KRAS Modulation.

Psaras(AM),McKay(SJ),Vasquez Vilela(J),Osp... Int J Mol Sci 2026-02-05

...CRISPR/Cas9 gene editing, Tet-ON inducible knockdown, polypurine reverse Hoogsteen hairpin (PPRH) oligonucleotides, and ...

High-Grade Serous Ovarian Carcinoma in the Genomics Era: Current Applications...

Lewis(ME),Caricato(C),Roberts(HL),Ganesan(... Int J Mol Sci 2026-02-06

...CRISPR)-based gene editing, neoantigen-guided immunotherapy and ovarian cancer vaccination indicate a promising future f...

Sorghum2035: A decadal vision for sorghum functional genomics and molecular b...

Yu(F),Tao(Y),Liu(L),Xie(P),Mace(E),Jordan(... Mol Plant 2026-03-02

...CRISPR/Cas9-mediated genome editing enhanced by morphogenic regulators, and the development of mutagenized populations f...

Metabolic Reprogramming and Ferroptosis: Unlocking New Therapeutic Frontiers ...

Huo(Y),Xia(Y),Zhang(Q),Li(Y),Zhao(Y),Li(Z)... Antioxid Redox Signal 2026-05-00

...CRISPR-based functional genomics, metabolomics, and AI-powered modeling represent new-age tools in defining ferroptosis ...

Genome data of Propionibacterium freudenreichii J117, a functional strain fro...

Deptula(P),Sihvola(J),Varmanen(P) Data Brief 2026-04-00

...CRISPR array, and pseudogenes. The raw sequencing data, genome assembly files, and annotation outputs are included in th...

Bio-orthogonal chemistry-based strategy to Turn-OFF CRISPR-Cas9 activity in s...

Pandit(B),Vangaveti(S),Sentre(JF),McClain(... NAR Mol Med 2026-01-00

The CRISPR-Cas9 system has become a widely used gene-editing tool. Here, we present a new method for small-molecule cont...

Feasibility of combining JAK1 gene editing via CRISPR-CasRx with EGCG-lactofe...

Zhu(H),Yu(H),Huang(M),Sun(P),Tang(Y),Zhang... Mater Today Bio 2026-04-00

...CRISPR-CasRx technology was employed to silence JAK1, and nanoparticles were constructed by encapsulating CasRx and siRN...

A pennycress transparent testa 8 knockout mutant has drastic changes in seed ...

Ding(X),Duckworth(S),Southworth(M),Lipton(... J Exp Bot 2026-03-27

...CRISPR genome editing to improve seed quality. We performed histochemical analyses on wild-type and tt8-2bp seeds at dif...

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