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ARID1A-Retained and SMARCA4-Aberrant Gastric Solid-Type Poorly Differentiated...

Umekita(S),Kiyozawa(D),Kawatoko(S),Sasaki(... Int J Surg Pathol 2026-06-12

...SMARCA4, and epithelial-mesenchymal transition (EMT) markers in it.MethodsWe retrospectively evaluated 116 patients with...

Distinct multiplex immunofluorescence-based immune and stromal marker express...

Li(H),Liang(Y),Wang(Y),Li(M),Su(Y),Chen(P)... Transl Lung Cancer Res 2026-05-31

...SMARCA4-deficient undifferentiated thoracic tumor (SMARCA4-UT) is a rare, rapidly progressive, and highly aggressive sub...

SMARCA4-Directed Treatment in Oncology Clinical Trials: A Review.

Hendee(S),Falchook(G) J Immunother Precis Oncol 2026-06-00

SMARCA4 is an ATPase subunit in the switch/sucrose non-fermentable complex (SWI/SNF), a chromatin-remodeling complex. SM...

Spatially-Resolved Multiomic Atlas of Leiomyosarcoma Identifies Two Clinicall...

Denu(RA),Zheng(Z),Jiang(Y),Satpati(S),Koch... bioRxiv 2026-05-26

...SMARCA4/2 inhibition as a promising therapeutic vulnerability for MES leiomyosarcomas. Together, this work defines two e...

Two cases of mosaic germline SVA insertions in SMARCB1: implications for rhab...

Raiti(L),Yuki(KE),Cinq-Mars(L),Higginbotha... NPJ Genom Med 2026-06-06

...SMARCA4. Genetic testing for this syndrome involves sequence and deletion/duplication analysis of these two genes. Stand...

Primary SMARCB1-deficient intestinal carcinoma: Clinicopathological and molec...

Shi(C),Li(SE),Jiang(N),Yan(M),Jiang(L) Pathol Res Pract 2026-10-00

...SMARCA4 expression but frequent loss of intestinal differentiation markers, including CK20 (2/9) and CDX2 (2/10). Molecu...

CT imaging features of pulmonary SMARCA4-deficient undifferentiated carcinoma...

Liu(Y),Lv(T),Han(L),Li(Y) Front Oncol None

...SMARCA4 (BRG1) nuclear expression with retained INI-1. Pulmonary SMARCA4-deficient undifferentiated carcinoma showed a r...

Spatial dissection of ADC/RPT targets defines heterogeneous expression landsc...

Reitsam(NG),Fincke(VE),Hernandez Ramirez(M... Neuro Oncol 2026-06-02

...SMARCA4), and dismal outcomes despite multimodal therapy. Refractory and relapsing RT remain almost uniformly fatal, and...

Transcriptomic profiling of epigenetic regulators and metabolic reprogramming...

Lopez-Pascual(A),Elurbide(J),Valbuena-Goir... Front Cell Dev Biol None

...SMARCA4), and erasers (HDAC1, HDAC3, KDM5C). MGs in OCM, TCA, and ACS pathways were dysregulated (up: GART, IDH2, TYMS; ...

Case Report: Synaptophysin-positive SMARCA4-deficient undifferentiated thorac...

Bai(CS),He(XW),Lin(S),Xu(BC),Yan(QX),Wang(... Front Oncol None

SMARCA4-deficient undifferentiated thoracic tumour (SMARCA4-UT) is a rare and highly aggressive malignancy with a poor p...

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