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TP53 BRCA1 CRISPR single-cell cancer

Fukagawa(Tatsuo) Epigenetics 2012-11-12

The kinetochore is formed on centromeric DNA as a key interface with microtubules from the mitotic spindle to achieve ac...

Samel(Anke),Cuomo(Alessandro),Bonaldi(Tizian… Proc Natl Acad Sci U S A 2012-08-27

Centromeres of eukaryotic chromosomes mark the site for kinetochore formation and microtubule attachment and are essenti...

Hemmat(Morteza),Wang(Boris T),Warburton(Pete… Mol Cytogenet 2012-10-22

Neocentromeres are rare human chromosomal aberrations in which a new centromere has formed in a previously non-centromer...

Foltz(Daniel R),Stukenberg(P Todd) Cell 2012-03-19

The centromere is a classic system to study epigenetic specification, and most research has focused on a specialized his...

Nishino(Tatsuya),Takeuchi(Kozo),Gascoigne(Ka… Cell 2012-03-19

The multiprotein kinetochore complex must assemble at a specific site on each chromosome to achieve accurate chromosome ...

Hsu(Mei-Hua),Liu(Chin-Yu),Lin(Chiao-Min),Che… Toxicol Appl Pharmacol 2012-06-28

2-(3-Methoxyphenyl)-5-methyl-1,8-naphthyridin-4(1H)-one (HKL-1), a 2-phenyl-1,8-naphthyridin-4-one (2-PN) derivative, wa...

Logarinho(Elsa),Maffini(Stefano),Barisic(Mar… Nat Cell Biol 2012-05-11

Loss of spindle-pole integrity during mitosis leads to multipolarity independent of centrosome amplification. Multipolar...

Wang(Jun-Xi),Zhang(Ying-Yao),Yu(Xue-Min),Jin… Asian Pac J Cancer Prev 2012-11-28

Centromere protein H (CENP-H) and Ki67 are overexpressed in some malignancies, but whether they are predictors of surviv...

Sardar(Harjinder S),Gilbert(Susan P) J Biol Chem 2012-10-18

Centromere protein E, CENP-E, is a kinetochore-associated kinesin-7 that establishes the microtubule-chromosome linkage ...

Maloney(Kristin A),Sullivan(Lori L),Matheny(… Proc Natl Acad Sci U S A 2012-10-31

Human centromeres are defined by megabases of homogenous alpha-satellite DNA arrays that are packaged into specialized c...

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