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Synthetic lethal targeting of DNA double-strand break repair deficient cells by…

Sultana(R),McNeill(DR),Abbotts(R),Mohammed(M… Int J Cancer 2012-11-15

...Rev1)]. ii) Human cancer cells: BRCA1 deficient (MDA-MB-436), BRCA1 proficient (MCF-7), BRCA2 deficient (CAPAN-1 and HeL...

Roles of the polymerase and BRCT domains of Rev1 protein in translesion DNA syn…

Otsuka(C),Kunitomi(N),Iwai(S),Loakes(D),Negi… Mutat Res 2005-10-15

Rev1p in yeast is essential for the translesion of abasic sites and 6-4 photoproducts. It plays a role as a translesion ...

Ubiquitylation of yeast proliferating cell nuclear antigen and its implications…

Haracska(L),Unk(I),Prakash(L),Prakash(S) Proc Natl Acad Sci U S A 2006-04-25

...Rev1. Contrary to the prevailing ideas that presume a role for PCNA ubiquitylation in the disruption of Poldelta's bindi...

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta.

Masutani(C),Kusumoto(R),Yamada(A),Dohmae(N),… Nature 1999-06-17

...Rev1 protein. We found that all XP-V cells examined carry mutations in their DNA polymerase eta gene. Recombinant human ...

The Saccharomyces cerevisiae rev6-1 mutation, which inhibits both the lesion by…

Zhang(H),Gibbs(PE),Lawrence(CW) Genetics 2006-08-00

...Rev1 and DNA polymerase eta, and the error-free, recombination-dependent component of this pathway, but has little effec...

[Anaplasma phagocytophila and protozoans of Babesia genus in dogs from endemic …

Skotarczak(B),Adamska(M),Rymaszewska(A),Supr… Wiad Parazytol 2004-00-00

...REV1 for Babesia. In 192 samples only two contained A. phagocytophila DNA. One of these samples originated from a health...

Quantitative analysis of the efficiency and mutagenic spectra of abasic lesion …

Sherrer(SM),Fiala(KA),Fowler(JD),Newmister(S… Nucleic Acids Res 2011-01-00

...Rev1, failed to generate full-length lesion bypass products after 3 h. The results indicate that hPolι generates mutatio...

Screening of potential target genes for cataract by analyzing mRNA expression p…

Zhao(Wenjuan),Zhao(Wenqing),Zhao(Jun),Wang(D… BMC Ophthalmol 2016-01-07

...REV1 were enriched in response to DNA damage stimulus. Furthermore, 89 DEGs and 99 gene pairs were mapped into the PPI n...

Functional screening reveals HORMAD1-driven gene dependencies associated with t…

Tarantino(D),Walker(C),Weekes(D),Pemberton(H… Oncogene 2022-00-00

...REV1, REV3L and REV7. Our data confirms that out-of-context somatic expression of HORMAD1 can lead to genomic instabilit...

The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution …

Gilea(AI),Magistrati(M),Notaroberto(I),Tiso(… IUBMB Life 2023-00-00

...Rev1 and Pol η, and to their genetic interactions with Mip1 necessary to maintain mtDNA stability and to avoid the accum...

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