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Evolutionary insights into the role of the essential centromere protein CAL1 in…

Phansalkar(Ragini),Lapierre(Pascal),Mellone(… Chromosome Res 2012-12-03

Centromeres are essential cis-elements on chromosomes that are crucial for the stable transmission of genetic informatio...

Kinesins and cancer.

Rath(Oliver),Kozielski(Frank) Nat Rev Cancer 2012-10-09

Kinesins are a family of molecular motors that travel unidirectionally along microtubule tracks to fulfil their many rol...

HACking the centromere chromatin code: insights from human artificial chromosom…

Bergmann(Jan H),Martins(Nuno M C),Larionov(V… Chromosome Res 2012-12-03

The centromere is a specialized chromosomal region that serves as the assembly site of the kinetochore. At the centromer...

The CENP-A nucleosome: a dynamic structure and role at the centromere.

Quénet(Delphine),Dalal(Yamini) Chromosome Res 2012-12-03

The centromere is a specialized locus that directs the formation of the kinetochore protein complex for correct chromoso...

Composition and organization of active centromere sequences in complex genomes.

Hayden(Karen E),Willard(Huntington F) BMC Genomics 2012-12-19

Centromeres are sites of chromosomal spindle attachment during mitosis and meiosis. While the sequence basis for centrom...

The split personality of CENP-A nucleosomes.

Westhorpe(Frederick G),Straight(Aaron F) Cell 2012-10-01

The composition and structure of centromeric nucleosomes, which contain the histone H3 variant CENP-A, is intensely deba...

Cell-cycle-dependent structural transitions in the human CENP-A nucleosome in v…

Bui(Minh),Dimitriadis(Emilios K),Hoischen(Ch… Cell 2012-10-01

In eukaryotes, DNA is packaged into chromatin by canonical histone proteins. The specialized histone H3 variant CENP-A p...

Mediator promotes CENP-a incorporation at fission yeast centromeres.

Carlsten(Jonas O),Szilagyi(Zsolt),Liu(Beidon… Mol Cell Biol 2012-11-26

At Schizosaccharomyces pombe centromeres, heterochromatin formation is required for de novo incorporation of the histone...

CENP-E--dependent BubR1 autophosphorylation enhances chromosome alignment and t…

Guo(Yige),Kim(Christine),Ahmad(Sana),Zhang(J… J Cell Biol 2012-10-16

How the state of spindle microtubule capture at the kinetochore is translated into mitotic checkpoint signaling remains ...

Multiple domains of human CLASP contribute to microtubule dynamics and organiza…

Patel(Kieren),Nogales(Eva),Heald(Rebecca) Cytoskeleton (Hoboken) 2012-07-19

Cytoplasmic linker associated proteins (CLASPs) comprise a class of microtubule (MT) plus end-binding proteins (+TIPs) t...

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