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TP53 BRCA1 CRISPR single-cell cancer

Yaginuma(Yuji),Eguchi(Ayami),Yoshimoto(Masaf… Oncology 2012-11-08

High-risk human papillomaviruses (HPVs) are etiologically linked to human cervical and oral cancers. HPV infection leads...

Smith(Amanda),Rutherford(Katherine),Benkel(B… Gene 2012-05-29

Tigger elements belong to the Tc1/Mariner family of DNA transposons which is remarkably widespread in nature with homolo...

Ohzeki(Jun-ichirou),Bergmann(Jan H),Kouprina… EMBO J 2012-07-16

The kinetochore is responsible for accurate chromosome segregation. However, the mechanism by which kinetochores assembl...

Valente(Luis P),Silva(Mariana C C),Jansen(La… Chromosome Res 2012-12-03

All living organisms require accurate mechanisms to faithfully inherit their genetic material during cell division. The ...

Lochmann(Berit),Ivanov(Dmitri) PLoS Genet 2012-09-25

During cell division, segregation of sister chromatids to daughter cells is achieved by the poleward pulling force of mi...

Hemmat(Morteza),Wang(Boris T),Warburton(Pete… Mol Cytogenet 2012-10-22

Neocentromeres are rare human chromosomal aberrations in which a new centromere has formed in a previously non-centromer...

Wang(Jun-Xi),Zhang(Ying-Yao),Yu(Xue-Min),Jin… Asian Pac J Cancer Prev 2012-11-28

Centromere protein H (CENP-H) and Ki67 are overexpressed in some malignancies, but whether they are predictors of surviv...

Sardar(Harjinder S),Gilbert(Susan P) J Biol Chem 2012-10-18

Centromere protein E, CENP-E, is a kinetochore-associated kinesin-7 that establishes the microtubule-chromosome linkage ...

Kinesins and cancer.

Rath(Oliver),Kozielski(Frank) Nat Rev Cancer 2012-10-09

Kinesins are a family of molecular motors that travel unidirectionally along microtubule tracks to fulfil their many rol...

Bergmann(Jan H),Martins(Nuno M C),Larionov(V… Chromosome Res 2012-12-03

The centromere is a specialized chromosomal region that serves as the assembly site of the kinetochore. At the centromer...

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