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Drosophila CENH3 is sufficient for centromere formation.

Mendiburo(María José),Padeken(Jan),Fülöp(Ste… Science 2012-01-25

CENH3 is a centromere-specific histone H3 variant essential for kinetochore assembly. Despite its central role in centro...

Dynamics of CENP-N kinetochore binding during the cell cycle.

Hellwig(Daniela),Emmerth(Stephan),Ulbricht(T… J Cell Sci 2012-04-02

Accurate chromosome segregation requires the assembly of kinetochores, multiprotein complexes that assemble on the centr...

Ring-like distribution of constitutive heterochromatin in bovine senescent cell…

Pichugin(Andrey),Beaujean(Nathalie),Vignon(X… PLoS One 2012-04-02

Cells that reach "Hayflick limit" of proliferation, known as senescent cells, possess a particular type of nuclear archi...

Assembling pieces of the centromere epigenetics puzzle.

González-Barrios(Rodrigo),Soto-Reyes(Ernesto… Epigenetics 2012-10-22

The centromere is a key region for cell division where the kinetochore assembles, recognizes and attaches to microtubule...

Assembly of Drosophila centromeric nucleosomes requires CID dimerization.

Zhang(Weiguo),Colmenares(Serafin U),Karpen(G… Mol Cell 2012-04-06

Centromeres are essential chromosomal regions required for kinetochore assembly and chromosome segregation. The composit...

CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome s…

Huang(Yuejia),Wang(Wenwen),Yao(Phil),Wang(Xi… J Biol Chem 2012-02-27

Mitotic chromosome segregation is orchestrated by the dynamic interaction of spindle microtubules with the kinetochore. ...

A homolog of male sex-determining factor SRY cooperates with a transposon-deriv…

Matsuda(Emiko),Sugioka-Sugiyama(Rie),Mizuguc… Proc Natl Acad Sci U S A 2012-01-26

Schizosaccharomyces pombe cells switch mating type by replacing genetic information at the expressed mat1 locus with seq...

First-time-in-human study of GSK923295, a novel antimitotic inhibitor of centro…

Chung(Vincent),Heath(Elisabeth I),Schelman(W… Cancer Chemother Pharmacol 2012-04-20

GSK923295 is an inhibitor of CENP-E, a key cellular protein important in the alignment of chromosomes during mitosis. Th...

Identification of a predominant co-regulation among kinetochore genes, prospect…

Reinhold(William C),Erliandri(Indri),Liu(Hon… PLoS One 2012-02-13

The NCI-60 cell line panel is the most extensively characterized set of cells in existence, and has been used extensivel...

The accuracy of survival time prediction for patients with glioma is improved b…

Bie(Li),Zhao(Gang),Cheng(Pui),Rondeau(Gaelle… PLoS One 2012-02-17

Identification of gene expression changes that improve prediction of survival time across all glioma grades would be cli...

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