The centromere kinesin motor protein CENP-E plays a crucial role in mitosis, and is an appealing molecular target in can...
Centromeres are defined by the presence of chromatin containing the histone H3 variant, CENP-A, whose assembly into nucl...
Centromeres direct faithful chromosome inheritance at cell division but are not defined by a conserved DNA sequence. Ins...
The centromere is the fundamental unit for insuring chromosome inheritance. This complex region has a distinct type of c...
Centromeres direct the assembly of kinetochores, microtubule-attachment sites that allow chromosome segregation on the m...
The diverse nature of eukaryotic centromere structure has led to a prevailing view that the kinetochore-chromatin interf...
The kinetochore is formed on centromeric DNA as a key interface with microtubules from the mitotic spindle to achieve ac...
Centromeres of eukaryotic chromosomes mark the site for kinetochore formation and microtubule attachment and are essenti...
Unlike most eukaryotes, a kinetochore is fully assembled early in the cell cycle in budding yeasts Saccharomyces cerevis...
The Mis18 complex has been identified as a critical factor for the centromeric localization of a histone H3 variant, cen...
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