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The rapidly evolving centromere-specific histone has stringent functional requi…

Ravi(Maruthachalam),Kwong(Pak N),Menorca(Ron… Genetics 2011-03-21

Centromeres control chromosome inheritance in eukaryotes, yet their DNA structure and primary sequence are hypervariable...

Consensus higher order repeats and frequency of string distributions in human g…

Paar(Vladimir),Basar(Ivan),Rosandić(Marija),… Curr Genomics 2011-07-14

Key string algorithm (KSA) could be viewed as robust computational generalization of restriction enzyme method. KSA enab...

Centromere protein A dynamics in human pluripotent stem cell self-renewal, diff…

Ambartsumyan(Gayane),Gill(Rajbir K),Perez(Si… Hum Mol Genet 2011-03-01

Human pluripotent stem cells (hPSCs) hold significant promise for use in regenerative medicine, or as a model to underst...

Fatal infections in a captive Pithecia irrorata (primate) by Porocephalus sp. (…

Pereira(W L A),Benigno(R N M),Silva(K S M) Vet Parasitol 2011-02-03

This work presents a case of sudden death of a non-human adult male primate, which belongs to the National Primate Cente...

FK228 induces mitotic catastrophe in A549 cells by mistargeting chromosomal pas…

Zhang(Xuhui),Zhang(Zhiyi),Chen(Guozhu),Zhao(… Acta Biochim Biophys Sin (Sha… 2011-03-03

Previous studies have shown that histone deacetylase inhibitors (HDACis) can kill cancer cells. In addition, HDACis can ...

The kinetochore protein Cenp-F is a potential novel target for zoledronic acid …

Brown(Hannah K),Ottewell(Penelope D),Coleman… J Cell Mol Med 2011-07-22

The anti-resorptive agent zoledronic acid inhibits key enzymes in the mevalonate pathway, disrupting post-translational ...

Centromere localization of INCENP-Aurora B is sufficient to support spindle che…

Becker(Markus),Stolz(Ailine),Ertych(Norman),… Cell Cycle 2011-03-31

During mitosis, the chromosomal passenger complex (CPC) comprising the Aurora B kinase, INCENP, survivin and borealin is...

Overlapping regulation of CenH3 localization and histone H3 turnover by CAF-1 a…

Lopes da Rosa(Jessica),Holik(John),Green(Eri… Genetics 2011-04-20

Accurate chromosome segregation is dependent on the centromere-specific histone H3 isoform known generally as CenH3, or ...

Detrimental incorporation of excess Cenp-A/Cid and Cenp-C into Drosophila centr…

Schittenhelm(Ralf B),Althoff(Friederike),Hei… J Cell Sci 2011-05-23

Propagation of centromere identity during cell cycle progression in higher eukaryotes depends critically on the faithful...

CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachme…

Itoh(Go),Kanno(Shin-ichiro),Uchida(Kazuhiko … EMBO J 2011-02-14

Proper attachment of microtubules to kinetochores is essential for accurate chromosome segregation. Here, we report a no...

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