Midthune(B),Tyan(SH),Walsh(JJ),Sarsoza(F),Eg… Mol Cell Neurosci 2012-04-00

...APLP2). Initial knock-out studies demonstrated that while single APP family gene deletions produced relatively mild phen...

Liang(C),Zhu(H),Xu(Y),Huang(L),Ma(C),Deng(W)… Brain Res 2012-05-21

...APLP2. Using miR-153 transgenic mouse model, we testified that miR-153 downregulated the expression of APP and APLP2 pro...

Xu(F),Previti(ML),Nieman(MT),Davis(J),Schmai… J Neurosci 2009-04-29

...APLP2 also regulates cerebral thrombosis risk. Recombinant purified KPI domains of AbetaPP and APLP2 both inhibit the pl...

Tuersuntuoheti(A),Li(Q),Teng(Y),Li(X),Huang(… Biochim Biophys Acta Mol Cell… 2023-10-00

...APLP2 increases the TGFBR2 protein level and sensitizes cells to TGF-β stimulation, while YWK-II/APLP2 overexpression de...

Zhang(X),Herrmann(U),Weyer(SW),Both(M),Mülle… PLoS One 2013-00-00

...APLP2) is largely unknown. Previous work suggests that lack of APP or APLP2 impairs synaptic plasticity and spatial lear...

Weyer(SW),Zagrebelsky(M),Herrmann(U),Hick(M)… Acta Neuropathol Commun 2014-03-31

...APLP2-KO neurons, combined APP/APLP2-DKO mutants showed an additional branching defect in proximal apical dendrites, ind...

Poelaert(BJ),Knoche(SM),Larson(AC),Pandey(P)… Cancers (Basel) 2021-03-26

...APLP2's role in cancer development. We found that APLP2 expression intensifies significantly during pancreatic cancer in...

Sandbrink(R),Masters(CL),Beyreuther(K) Ann N Y Acad Sci 1996-01-17

...APLP2 transcripts are highly expressed in neurons, in contrast to KPI-APPs, while L-APLP2 mRNA isoforms lacking the 12 a...

Butkinaree(C),Canuel(M),Essalmani(R),Poirier… J Biol Chem 2015-07-24

...APLP2 or sortilin both ex vivo and in mice. Interestingly, when co-expressed with PCSK9, both APLP2 and sortilin were ta...

von der Kammer(H),Löffler(C),Hanes(J),Klaudi… Genomics 1994-03-15

The human amyloid precursor-like protein APLP2 is a highly conserved homologue of a sequence-specific DNA-binding mouse ...