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Molecular anatomy of PLK1 master docking motifs.

Ren(L),Esposito-Verza(A),Gasper(R),Pesenti... Nat Commun 2026-05-11

The Polo-box domain (PBD) localizes Polo-like kinase 1 (PLK1) near mitotic substrates required for chromosome biorientat...

Cohesin and its regulation promote monopolar kinetochore orientation at meios...

Singh(DK),Mahlandt(A),Durand(S),Jolivet(S)... Curr Biol 2026-04-20

The first division of meiosis is unique in its capacity to halve the ploidy of future gametes. To this end, one key inno...

Time-Dependent Anti-inflammatory and Antibacterial Dual-Functional Suture Fib...

Lu(J),Zhong(W),Ma(H),Pan(L),Zhou(Z),Hou(K)... ACS Appl Mater Interfaces 2026-04-29

...CeNPs) into poly(lactic acid) (polylactic acid) via melt spinning, followed by surface coating with copper alginate. The...

The dynamics of centromere assembly and disassembly during quiescence.

Marescal(O),Su(KC),Moodie(B),Taylor(NJL),C... J Cell Biol 2026-06-01

Quiescence is a state in which cells undergo a proliferative arrest while maintaining their capacity to divide again. He...

Assembly and phosphoregulatory mechanisms of the budding yeast outer kinetoch...

Turner(NN),Zhang(Z),Yang(J),Muir(KW),McLau... J Cell Biol 2026-05-04

During mitosis and meiosis, kinetochores mediate interactions between chromosomes and spindle microtubules. Kinetochores...

Haplotype-resolved centromeric chromatin organization from a complete diploid...

Xu(Y),Loucks(H),Menendez(J),Ryabov(F),Luca... bioRxiv 2026-03-31

Centromeres ensure proper chromosome segregation during cell division, yet the organization and regulation of centromeri...

SIRT1 haploinsufficiency recapitulates age-associated subfertility through sp...

Iniesta-Cuerda(M),Valentova(I),Moravec(J),... Biol Direct 2026-03-25

Advanced paternal age compromises male fertility and correlates to a decline of the deacetylase SIRT1 activity, a centra...

The Postnatal Lung Maturation Disrupted by Increased Pulmonary Blood Flow and...

Zheng(S),Wang(Z),Xue(Y),Zhang(H),Xiao(Y),H... JACC Asia 2026-08-00

Increased pulmonary blood flow (IPF) from congenital heart diseases causes pediatric pulmonary hypertension and respirat...

Mitotic BLM functions are required to maintain genomic stability.

Hamann(TE),Wieland(A),Mohseni(F),Vukušić(K... Nucleic Acids Res 2026-02-24

The BLM helicase is a critical genome maintenance protein involved in diverse cellular processes including DNA replicati...

Oxidative Stress and Hormone-Regulated Dermal Papilla Cell-Targeted Nanomodul...

Lan(L),Zhou(Q),Pan(S),Liu(H),Du(Y),Guan(C)... Biomater Res None

...CeNPs down-regulated senescence markers (p16/pRb) via dual-pathway synergy, effectively reversing cellular senescence an...

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