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Genetic variability of genes in NER pathway influences the treatment outcome of…

Xue(Ming-Hui),Li(Guang-Yan),Wu(Xin-Jun),Zhan… Int J Clin Exp Pathol 2016-04-21

We performed a study to investigate the role of ERCC1, ERCC2, ERCC5, XPA and XPC polymorphisms from perspective of the w...

Genetic variability of DNA repair mechanisms influences chemotherapy outcome of…

Yu(Hai),Wu(Xinghua),Zhang(Yonggang),Jin(Zhih… Int J Clin Exp Pathol 2016-09-26

...ERCC2 rs1799793 were correlated with shorter survival of gastric cancer. In conclusion, ERCC1 rs11615, rs2298881 and ERC...

Pharmacogenomic assessment of Mexican and Peruvian populations.

Marsh(Sharon),King(Cristi R),Van Booven(Dere… Pharmacogenomics 2016-01-19

...ERCC2 K751Q, GSTP1 I105V, TPMT 238G>C, TPMT 460G>A, TPMT 719A>G, TYMS TSER, UGT1A1*28 and UGT1A1 -3156G>A) in 81 Peruvia...

Influence of Morinda citrifolia (Noni) on Expression of DNA Repair Genes in Cer…

Gupta(Rakesh Kumar),Bajpai(Deepti),Singh(Nee… Asian Pac J Cancer Prev 2016-01-26

...ERCC2, and ERCC4 and base excision repair gene XRCC1 was increased 4 fold, 8.9 fold, 4 fold, and 5.5 fold, respectively,...

Association of chromosome 19 to lung cancer genotypes and phenotypes.

Wang(Xiangdong),Zhang(Yong),Nilsson(Carol L)… Cancer Metastasis Rev 2016-10-31

...ERCC2, XRCC1), TGFβ1 pathway activation genes (TGFB1, LTBP4), Dyrk1B, and potential oncogenesis protector genes such as ...

New mutation in the mouse Xpd/Ercc2 gene leads to recessive cataracts.

Kunze(Sarah),Dalke(Claudia),Fuchs(Helmut),Kl… PLoS One 2016-02-25

...Ercc2 gene leading to a Ser737Pro exchange. During embryonic development, the mutant eyes did not show major changes. Po...

GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in …

Kuschal(Christiane),Botta(Elena),Orioli(Dona… Am J Hum Genet 2016-08-29

...ERCC2, which encodes the XPD subunit of TFIIH, but not in XP cells with ERCC2 mutations. Our findings support the theory...

Prognostic value of ERCC1 and ERCC2 gene polymorphisms in patients with gastric…

Mo(Juanmei),Luo(Min),Cui(Jiandong),Zhou(Shao… Int J Clin Exp Pathol 2016-11-01

We conducted a prospective study to analyze whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene pol...

Genetic variability of ERCC1 and ERCC2 influences treatment outcomes in gastric…

Yu(W H),Wang(Y X),Guo(J Q),Wang(Y L),Zheng(J… Genet Mol Res 2016-10-11

We performed a study to investigate the role of ERCC1 (rs11615, rs2298881, and rs3212986) and ERCC2 (rs13181, rs238406, ...

Polymorphism of CYP3A4 and ABCB1 genes increase the risk of neuropathy in breas…

Kus(Tulay),Aktas(Gokmen),Kalender(Mehmet Emi… Onco Targets Ther 2016-08-30

...ERCC2, FGFR4, TP53, ERBB2, and CYP2C8 genes. Taxane-induced neurotoxicity during the treatment was evaluated according t...

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