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Mismatch repair deficiency in ovarian cancer -- molecular characteristics and c…

Xiao(Xue),Melton(David W),Gourley(Charlie) Gynecol Oncol 2014-04-11

...PMS1 and PMS2) occurs in up to 29% of cases. Both mutational and expression data suggest that MMR deficiency is more com...

Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substra…

Srivatsan(Anjana),Bowen(Nikki),Kolodner(Rich… J Biol Chem 2014-05-21

...Pms1 recruitment. Msh2-Msh3 formed sliding clamps and recruited Mlh1-Pms1 on +1, +2, +3, and +4 insertion/deletions and ...

Yeast mutator phenotype enforced by Arabidopsis PMS1 expression.

Galles(Celina),Spampinato(Claudia P) Mol Biol Rep 2014-03-03

...PMS1 in yeast and plants and MLH1-PMS2 in humans. We here report the effect the expression of Arabidopsis PMS1 protein e...

PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1…

Goellner(Eva M),Smith(Catherine E),Campbell(… Mol Cell 2014-10-13

...Pms1 recruitment, including Exonuclease 1 (Exo1)-dependent and -independent pathways. We identified 14 mutations in POL3...

Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 e…

Gueneau(Emeric),Dherin(Claudine),Legrand(Pie… Nat Struct Mol Biol 2013-06-11

...Pms1 heterodimer) C-terminal domain (CTD) from Saccharomyces cerevisiae, alone and in complex with fragments derived fro...

Distinct cancer-specific survival in metastatic prostate cancer patients classi…

Tsuchiya(Norihiko),Matsui(Shigeyuki),Narita(… Genes Cancer 2013-08-15

...PMS1, GATA3, IL13, CASP8, and IGF1, were identified to have a statistically significant association with cancer-specific...

Classification, diagnosis, and management of idiopathic inflammatory myopathies.

Lazarou(Ilias N),Guerne(Pierre-André) J Rheumatol 2013-12-10

...PMS1, frequently associated with distinct and well-defined clinicopathological features, allowed for significant improve...

Engineered disulfide-forming amino acid substitutions interfere with a conforma…

Hargreaves(Victoria V),Putnam(Christopher D)… J Biol Chem 2013-02-07

...Pms1. It has been inferred from these observations that ATP induces conformational changes in Msh2-Msh6; however, the na...

The unstructured linker arms of Mlh1-Pms1 are important for interactions with D…

Plys(Aaron J),Rogacheva(Maria V),Greene(Eric… J Mol Biol 2012-11-06

...Pms1. Cleavage of the Mlh1 linker arm in vitro resulted in a defect in Mlh1-Pms1 DNA binding activity, and in vivo prote...

The cumulative effects of polymorphisms in the DNA mismatch repair genes and to…

Vogelsang(Matjaz),Wang(Yabing),Veber(Nika),M… PLoS One 2012-09-19

...PMS1 rs5742938 (GG versus AA or AG: OR = 1.73; 95% CI: 1.07-2.79) and MLH3 rs28756991 (AA or GA versus GG: OR = 2.07; 95...

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