Lee(Joon),Dunphy(William G) Mol Biol Cell 2013-11-14

...Rad17 and MRN leads to a further, essentially complete, reduction in the activation of Chk1. Thus, Rad17 and MRN act in ...

Shiotani(Bunsyo),Nguyen(Hai Dang),Håkansson(… Cell Rep 2013-12-16

...Rad17-independent but Nbs1-dependent manner in vivo and in vitro. Importantly, the role of Nbs1 in RPA32 phosphorylation...

Tomida(Junya),Itaya(Akiko),Shigechi(Tomoko),… Nucleic Acids Res 2013-11-04

...RAD17 and TOPBP1 is largely dispensable for the FA pathway activation. Indeed DT40 mutant cells lacking both RAD17 and F...

Ho(Hsuan-Chung),Burgess(Sean M) PLoS Genet 2012-02-22

...Rad17 and the ATR ortholog Mec1, which respond to the presence of single-stranded DNA. An N-terminal deletion of Xrs2 re...

Weigman(Victor J),Chao(Hann-Hsiang),Shabalin… Breast Cancer Res Treat 2012-11-06

...RAD17, or RAD17/RAD50, in immortalized human mammary epithelial cell lines caused increased sensitivity to a PARP inhibi...

Fujinaka(Yoshihiko),Matsuoka(Kazuaki),Iimori… DNA Repair (Amst) 2012-09-10

...Rad17-deficient cells. These results suggest that Rad9- and Rad17-independent activation of the ATR-Chk1 signaling pathw...

Perego(Paola),Cossa(Giacomo),Tinelli(Stella)… Biochem Pharmacol 2012-01-20

...RAD17, which participates in the stabilization of collapsed replication forks. The expression of dominant-negative PARP1...

Reha-Krantz(Linda J),Siddique(Md Shahjahan P… Genetics 2012-04-11

...Rad17-Mec3, and the Rad24-dependent clamp loader, but does not depend on Mrc1, which acts as the signaling adapter for t...

Chung(Inn),Leonhardt(Heinrich),Rippe(Karsten) J Cell Sci 2012-03-25

...Rad17 and Rad51 were less efficient in APB nucleation but were recruited to preassembled APBs. The artificially created ...

Lindsey-Boltz(Laura A),Reardon(Joyce T),Wold… J Biol Chem 2012-12-28

...Rad17, has the same requirements and that RPA is also phosphorylated in this system. At high p53 or Rad17 concentrations...