In higher eukaryotes, the centromere is epigenetically specified by the histone H3 variant Centromere Protein-A (CENP-A)...
Human centromeres contain multi-megabase-sized arrays of alpha satellite DNA, a family of satellite DNA repeats based on...
Epigenetic mechanisms regulate genome activation in diverse events, including normal development and cancerous transform...
Highly Expressed in Cancer protein 1 (Hec1) is a constituent of the Ndc80 complex, a kinetochore component that has been...
Advances in immunofluorescence assay development paved the way for the simultaneous detection of several antibodies in o...
Proper assembly of the kinetochore, a multi-protein complex that mediates attachment of centromere DNA to spindle microt...
Uracil is removed from DNA by the conserved enzyme uracil DNA N-glycosylase (UNG). Previously, we observed that inhibiti...
The centromere is a unique chromosomal locus that ensures accurate segregation of chromosomes during cell division by di...
Centrosomes are closely associated with the nuclear envelope (NE) throughout the cell cycle and this association is main...
RrS1-like sequences of water frogs (genus Pelophylax) display varied genomic organization, whereas the centromeric hybri...
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