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Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP.

Hu(Hao),Liu(Yang),Wang(Mingzhu),Fang(Junnan)… Genes Dev 2011-06-24

In higher eukaryotes, the centromere is epigenetically specified by the histone H3 variant Centromere Protein-A (CENP-A)...

Genomic size of CENP-A domain is proportional to total alpha satellite array si…

Sullivan(Lori L),Boivin(Christopher D),Mravi… Chromosome Res 2011-09-20

Human centromeres contain multi-megabase-sized arrays of alpha satellite DNA, a family of satellite DNA repeats based on...

A small GTPase molecular switch regulates epigenetic centromere maintenance by …

Lagana(Anaïck),Dorn(Jonas F),De Rop(Valérie)… Nat Cell Biol 2011-01-06

Epigenetic mechanisms regulate genome activation in diverse events, including normal development and cancerous transform...

Abnormal kinetochore-generated pulling forces from expressing a N-terminally mo…

Mattiuzzo(Marta),Vargiu(Giulia),Totta(Pieran… PLoS One 2011-08-02

Highly Expressed in Cancer protein 1 (Hec1) is a constituent of the Ndc80 complex, a kinetochore component that has been...

Multiplex assessment of non-organ-specific autoantibodies with a novel microbea…

Grossmann(Kai),Roggenbuck(Dirk),Schröder(Chr… Cytometry A 2011-05-12

Advances in immunofluorescence assay development paved the way for the simultaneous detection of several antibodies in o...

CaMtw1, a member of the evolutionarily conserved Mis12 kinetochore protein fami…

Roy(Babhrubahan),Burrack(Laura S),Lone(Musee… Mol Microbiol 2011-07-15

Proper assembly of the kinetochore, a multi-protein complex that mediates attachment of centromere DNA to spindle microt...

Uracil DNA N-glycosylase promotes assembly of human centromere protein A.

Zeitlin(Samantha G),Chapados(Brian R),Baker(… PLoS One 2011-07-05

Uracil is removed from DNA by the conserved enzyme uracil DNA N-glycosylase (UNG). Previously, we observed that inhibiti...

Structural basis for recognition of centromere histone variant CenH3 by the cha…

Zhou(Zheng),Feng(Hanqiao),Zhou(Bing-Rui),Ghi… Nature 2011-06-09

The centromere is a unique chromosomal locus that ensures accurate segregation of chromosomes during cell division by di...

A Nup133-dependent NPC-anchored network tethers centrosomes to the nuclear enve…

Bolhy(Stéphanie),Bouhlel(Imène),Dultz(Elisa)… J Cell Biol 2011-07-04

Centrosomes are closely associated with the nuclear envelope (NE) throughout the cell cycle and this association is main...

RrS1-like sequences of water frogs from Central Europe and around the Aegean Se…

Marracci(Silvia),Michelotti(Valentina),Guex(… J Mol Evol 2011-09-07

RrS1-like sequences of water frogs (genus Pelophylax) display varied genomic organization, whereas the centromeric hybri...

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