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Characterisation of histone variant distribution in human embryonic stem cells …

Shaw(Margaret L),Williams(Evan J),Hawes(Susa… Mol Reprod Dev 2010-01-11

Recent studies, primarily in mouse embryonic stem cells, have highlighted the unique chromatin state of pluripotent stem...

Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microt…

Maffini(Stefano),Maia(Ana R R),Manning(Amity… Curr Biol 2010-01-14

Efficient chromosome segregation during mitosis relies on the coordinated activity of molecular motors with proteins tha...

CENPA overexpression promotes genome instability in pRb-depleted human cells.

Amato(Angela),Schillaci(Tiziana),Lentini(Lau… Mol Cancer 2010-04-29

Aneuploidy is a hallmark of most human cancers that arises as a consequence of chromosomal instability and it is frequen...

Anti-CENP-B antibodies are associated with prolonged survival in breast cancer.

Atalay(Can),Dogan(Lutfi),Atalay(Gonca) Future Oncol 2010-06-14

Presence of a relationship between autoimmunity and malignant diseases has been investigated for a long time. Anti-SS-B ...

Molecular control of kinetochore-microtubule dynamics and chromosome oscillatio…

Amaro(Ana C),Samora(Catarina P),Holtackers(R… Nat Cell Biol 2010-04-26

Chromosome segregation in metazoans requires the alignment of sister kinetochores on the metaphase plate. During chromos...

The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres.

Sekulic(Nikolina),Bassett(Emily A),Rogers(Da… Nature 2010-10-15

Centromeres are specified epigenetically, and the histone H3 variant CENP-A is assembled into the chromatin of all activ...

Aurora kinases and protein phosphatase 1 mediate chromosome congression through…

Kim(Yumi),Holland(Andrew J),Lan(Weijie),Clev… Cell 2010-09-01

Opposing roles of Aurora kinases and protein phosphatase 1 (PP1) during mitosis have long been suggested. Here, we demon...

Centromeres: assembling and propagating epigenetic function.

Glynn(Macdara),Kaczmarczyk(Agnieszka),Prende… Subcell Biochem 2010-06-01

...CENPs) associates with centromeric chromatin throughout the cell cycle and are required for kinetochore function. Unlike...

The Nup107-160 nucleoporin complex promotes mitotic events via control of the l…

Platani(Melpomeni),Santarella-Mellwig(Rachel… Mol Biol Cell 2010-03-09

The human Nup107-160 nucleoporin complex plays a major role in formation of the nuclear pore complex and is localized to...

Histone variant H2A.Z regulates centromere silencing and chromosome segregation…

Hou(Haitong),Wang(Yu),Kallgren(Scott P),Thom… J Biol Chem 2010-02-08

The incorporation of histone variant H2A.Z into nucleosomes plays essential roles in regulating chromatin structure and ...

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