Recent studies, primarily in mouse embryonic stem cells, have highlighted the unique chromatin state of pluripotent stem...
Efficient chromosome segregation during mitosis relies on the coordinated activity of molecular motors with proteins tha...
Aneuploidy is a hallmark of most human cancers that arises as a consequence of chromosomal instability and it is frequen...
Presence of a relationship between autoimmunity and malignant diseases has been investigated for a long time. Anti-SS-B ...
Chromosome segregation in metazoans requires the alignment of sister kinetochores on the metaphase plate. During chromos...
Centromeres are specified epigenetically, and the histone H3 variant CENP-A is assembled into the chromatin of all activ...
Opposing roles of Aurora kinases and protein phosphatase 1 (PP1) during mitosis have long been suggested. Here, we demon...
...CENPs) associates with centromeric chromatin throughout the cell cycle and are required for kinetochore function. Unlike...
The human Nup107-160 nucleoporin complex plays a major role in formation of the nuclear pore complex and is localized to...
The incorporation of histone variant H2A.Z into nucleosomes plays essential roles in regulating chromatin structure and ...
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