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Centromere activity in dicentric small supernumerary marker chromosomes.

Ewers(Elisabeth),Yoda(Kinya),Hamid(Ahmed B),… Chromosome Res 2010-10-18

Twenty-five dicentric small supernumerary marker chromosomes (sSMC) derived from #13/21, #14, #15, #18, and #22 were stu...

Dual recognition of CENP-A nucleosomes is required for centromere assembly.

Carroll(Christopher W),Milks(Kirstin J),Stra… J Cell Biol 2010-08-12

...CENPs examined, including CENP-K, CENP-H, CENP-I, and CENP-T, and led to a partial reduction in centromeric CENP-A. We p...

Vertebrate kinetochore protein architecture: protein copy number.

Johnston(Katherine),Joglekar(Ajit),Hori(Tets… J Cell Biol 2010-07-08

To define the molecular architecture of the kinetochore in vertebrate cells, we measured the copy number of eight kineto...

Aurora kinases and protein phosphatase 1 mediate chromosome congression through…

Kim(Yumi),Holland(Andrew J),Lan(Weijie),Clev… Cell 2010-09-01

Opposing roles of Aurora kinases and protein phosphatase 1 (PP1) during mitosis have long been suggested. Here, we demon...

Telomere disruption results in non-random formation of de novo dicentric chromo…

Stimpson(Kaitlin M),Song(Ihn Young),Jauch(An… PLoS Genet 2010-12-28

Genome rearrangement often produces chromosomes with two centromeres (dicentrics) that are inherently unstable because o...

Epigenetic centromere specification directs aurora B accumulation but is insuff…

Bassett(Emily A),Wood(Stacey),Salimian(Kevan… J Cell Biol 2010-08-27

...CENPs at the foundation of the kinetochore is intact at a human neocentromere lacking repetitive alpha-satellite DNA. Ho...

Correlation of antinuclear antibody immunofluorescence patterns with immune pro…

Sebastian(Wendy),Roy(Atanu),Kini(Usha),Mulli… Indian J Pathol Microbiol 2010-11-16

Immunity status, individual response to disease and types of antibodies produced are well known to vary from person to p...

SUMOylation modulates the function of Aurora-B kinase.

Fernández-Miranda(Gonzalo),Pérez de Castro(I… J Cell Sci 2010-12-02

Aurora kinases are central regulators of mitotic-spindle assembly, chromosome segregation and cytokinesis. Aurora B is a...

Centromere identity: a challenge to be faced.

Mehta(Gunjan D),Agarwal(Meenakshi P),Ghosh(S… Mol Genet Genomics 2010-08-06

The centromere is a genetic locus, required for faithful chromosome segregation, where spindle fibers attach to the chro...

[Effect of siRNA targeting centromere protein-A gene on biological behavior of …

Li(Yong-mei),Zhu(Zhi),Chen(Ying),Luo(Zhi-gan… Zhonghua Bing Li Xue Za Zhi 2010-09-13

To study the influence of siRNA inhibition of CENP-A expression on the biological behavior of HepG2 cells.,Three pairs o...

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