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Motor-independent targeting of CLASPs to kinetochores by CENP-E promotes microt…

Maffini(Stefano),Maia(Ana R R),Manning(Amity… Curr Biol 2010-01-14

Efficient chromosome segregation during mitosis relies on the coordinated activity of molecular motors with proteins tha...

Primary biliary cirrhosis (PBC), PBC autoantibodies, and hepatic parameter abno…

Assassi(Shervin),Fritzler(Marvin J),Arnett(F… J Rheumatol 2010-02-11

To investigate the diagnostic accuracy of antimitochondrial antibodies (AMA), sp100, and gp210 antibodies for primary bi...

Human condensin function is essential for centromeric chromatin assembly and pr…

Samoshkin(Alexander),Arnaoutov(Alexei),Janse… PLoS One 2010-01-19

Condensins I and II in vertebrates are essential ATP-dependent complexes necessary for chromosome condensation in mitosi...

Conservation and divergence of centromere specification in yeast.

Ishii(Kojiro) Curr Opin Microbiol 2010-01-12

Centromeres are specialized structures on eukaryotic chromosomes that couple chromosome movements to spindle microtubule...

Reduced expression of cenp-e in human hepatocellular carcinoma.

Liu(Zijie),Ling(Kang),Wu(Xia),Cao(Ju),Liu(Bi… J Exp Clin Cancer Res 2010-03-09

CENP-E, one of spindle checkpoint proteins, plays a crucial role in the function of spindle checkpoint. Once CENP-E expr...

Centromeres: assembling and propagating epigenetic function.

Glynn(Macdara),Kaczmarczyk(Agnieszka),Prende… Subcell Biochem 2010-06-01

...CENPs) associates with centromeric chromatin throughout the cell cycle and are required for kinetochore function. Unlike...

Histone variant H2A.Z regulates centromere silencing and chromosome segregation…

Hou(Haitong),Wang(Yu),Kallgren(Scott P),Thom… J Biol Chem 2010-02-08

The incorporation of histone variant H2A.Z into nucleosomes plays essential roles in regulating chromatin structure and ...

Centromeres: the wild west of the post-genomic age.

Zeitlin(Samantha G) Epigenetics 2010-05-25

Centromeric repetitive DNA is the largest missing piece of the Human Genome Project. Rather than being necessary or suff...

HJURP binds CENP-A via a highly conserved N-terminal domain and mediates its de…

Shuaib(Muhammad),Ouararhni(Khalid),Dimitrov(… Proc Natl Acad Sci U S A 2010-03-12

The human histone H3 variant, CENP-A, replaces the conventional histone H3 in centromeric chromatin and, together with c...

Identification of CENP-V as a novel microtubule-associating molecule that activ…

Honda(Zen-Ichiro),Suzuki(Takeshi),Honda(Hiro… Genes Cells 2010-02-04

The activation mechanisms of Src family kinases (SFKs) involve the dissociation of the intramolecular interaction betwee...

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