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Symmetric Assembly of a Decameric Subcomplex in Human Multi-tRNA Synthetase Com…

Cho(HY),Lee(HJ),Choi(YS),Kim(DK),Jin(KS),Kim… J Mol Biol 2019-00-08

...AIMP2, and AIMP3. In the crystal structure, the four GST domains are assembled in the order of MRS-AIMP3-EPRS-AIMP2, and...

Quantitative analysis of nasal transcripts reveals potential biomarkers for Par…

Kim(H),Kang(SJ),Jo(YM),Kim(MS),Lee(Y),Cho(SH… Sci Rep 2019-00-31

...AIMP2 in PD patients when compared to controls (cutoff value = 1.753 for with 84.2% sensitivity and 84.6% specificity; 0...

Fluorescence-Based Analysis of Noncanonical Functions of Aminoacyl-tRNA Synthet…

Kim(M),Kim(H),Kim(D),Park(C),Huh(Y),Jung(J),… Materials (Basel) 2019-04-01

...AIMP2/p38, and AIMP3/p18. The canonical functions of AIMPs include not only protein synthesis via multisynthetase comple...

Deubiquitinase USP29 Governs MYBBP1A in the Brains of Parkinson's Disease Patie…

Jo(A),Lee(Y),Park(CH),Shin(JH) J Clin Med 2019-12-24

...Aimp2 knockdown mice, whereas the upregulation of MYBBP1A was observed in the VM of inducible AIMP2 transgenic mice, as ...

The RARS-MAD1L1 Fusion Gene Induces Cancer Stem Cell-like Properties and Therap…

Zhong(Q),Liu(ZH),Lin(ZR),Hu(ZD),Yuan(L),Liu(… Clin Cancer Res 2018-00-01

...AIMP2, which resulted in activation of FUBP1/c-Myc pathway. The silencing of FUBP1 or the administration of a c-Myc inhi...

Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 simulta…

Schwarz(MA),Lee(DD),Bartlett(S) Int J Biochem Cell Biol 2018-00-00

...AIMP2, all three proteins appear to compose a core docking structure for the eight ARS in the MSC complex.

Homozygosity for a nonsense variant in AIMP2 is associated with a progressive n…

Shukla(A),Das Bhowmik(A),Hebbar(M),Rajagopal… J Hum Genet 2018-01-00

...AIMP2. The variant lies in a common homozygous region of 940 kb on chromosome 7 and is likely to have been inherited fro...

AIMP2-DX2 Promotes the Proliferation, Migration, and Invasion of Nasopharyngeal…

Cao(Q),Zhang(J),Zhang(T) Biomed Res Int 2018-00-00

...AIMP2-DX2 in NPC development remain to be elucidated. Here, we found that the mRNA expression level of AIMP2-DX2 was sig...

The c-Abl inhibitor in Parkinson disease.

Zhou(ZH),Wu(YF),Wang(XM),Han(YZ) Neurol Sci 2017-04-00

...AIMP2 (aminoacyl-tRNA synthetase-interacting multifunctional protein type2), FBP1 (fuse-binding protein 1), and synphili...

VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clear…

Yun(SP),Kim(H),Ham(S),Kwon(SH),Lee(GH),Shin(… Cell Death Dis 2017-00-06

...AIMP2 dependent. These findings provide new mechanistic insights into the role of VPS35 in the regulation of AIMP2 level...

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