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Testing the metal of ERCC2 in predicting the response to platinum-based therapy.

Turchi(John J),Woods(Derek S),VanderVere-Car… Cancer Discov 2016-05-16

...ERCC2 that correlate with the response to platinum-based therapy. This work provides evidence that defects in NER can be...

Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive…

Van Allen(Eliezer M),Mouw(Kent W),Kim(Philip… Cancer Discov 2016-05-16

...ERCC2 mutants in an ERCC2-deficient cell line failed to rescue cisplatin and UV sensitivity compared with wild-type ERCC...

A systematic review and meta-analysis of somatic and germline DNA sequence biom…

Findlay(J M),Middleton(M R),Tomlinson(I) Ann Oncol 2016-02-09

...ERCC2 rs1799793, TP53 rs1042522, MDM2 rs2279744, TYMS rs34743033, ABCB1 rs1045642 and MTHFR rs1801133. Twelve germline m...

Association between DNA repair gene polymorphisms and risk of glioma: a systema…

Adel Fahmideh(Maral),Schwartzbaum(Judith),Fr… Neuro Oncol 2015-01-28

...ERCC2 (XPD), and XRCC1 may increase the risk of glioma, while polymorphisms rs1136410 (OR = 0.78 (0.68-0.89), P = .0004)...

Association of single-nucleotide polymorphisms in ERCC1 and ERCC2 with glioma r…

Hui(Lei),Yue(Shuangzhu),Gao(Guojun),Chang(Ha… Tumour Biol 2015-01-13

...ERCC2) on the glioma risk in a Chinese population, and investigate the gene-environmental interaction for the cancer ris...

Association of ERCC1 C8092A and ERCC2 Lys751Gln polymorphisms with the risk of …

Xin(Yu),Hao(Shuyu),Lu(Jiapeng),Wang(Qianyi),… PLoS One 2015-07-31

...ERCC2 Lys751Gln polymorphism, no significant association was found between ERCC2 Lys751Gln polymorphism and the risk of ...

[Study on the effect of deficient ERCC2/XPD gene on the repair of DNA damage in…

Guan(Yangyang),Xiao(Sha),Li(Dandan),Xue(Ping… Wei Sheng Yan Jiu 2015-03-30

...ERCC2/XPD defective, indicating us that ERCC2/XPD play a critical role in the repair process of DNA damage induced by UV...

[Relationship between ERCC2 single nucleotide polymorphisms and male idiopathic…

Liu(Chun-Lian),Jiao(Hai-Yan),Ma(Qiang),Wu(Xi… Zhonghua Nan Ke Xue 2015-05-16

To explore the influence of the DNA repair gene ERCC2 single nucleotide polymorphisms (SNPs) rs13181, rs1618536, and rs1...

Associations of polymorphisms in DNA repair genes and MDR1 gene with chemothera…

Du(Yan),Su(Tong),Zhao(Lijun),Tan(Xiaojie),Ch… PLoS One 2015-01-29

...ERCC2) rs13181, X-ray repair cross complementing group 1 (XRCC1) rs25487, XRCC3 rs1799794, and breast cancer susceptibil...

Genetic variability in DNA repair proteins in age-related macular degeneration.

Blasiak(Janusz),Synowiec(Ewelina),Salminen(A… Int J Mol Sci 2015-04-21

...ERCC2), XRCC1 and ERCC6 (CSB) have also been reported to be associated with AMD. These data confirm the importance of th...

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