CENP-F (also named mitosin) is a multifunctional protein of 350 kDa. In interphase, it is a nuclear protein, whereas in ...
Mps1 is an essential component of the spindle assembly checkpoint. In this study, we describe a novel Mps1 inhibitor, AZ...
Some patients with systemic sclerosis express autoantibodies to centromere-associated protein A (CENP-A), but the exact ...
...CENPs examined, including CENP-K, CENP-H, CENP-I, and CENP-T, and led to a partial reduction in centromeric CENP-A. We p...
Twenty-five dicentric small supernumerary marker chromosomes (sSMC) derived from #13/21, #14, #15, #18, and #22 were stu...
The centromere is a genetic locus, required for faithful chromosome segregation, where spindle fibers attach to the chro...
To define the molecular architecture of the kinetochore in vertebrate cells, we measured the copy number of eight kineto...
A longstanding question in centromere biology has been the organization of CENP-A-containing chromatin and its implicati...
Proper centromere function is critical to maintain genomic stability and to prevent aneuploidy, a hallmark of tumors and...
The spindle assembly checkpoint (SAC) prevents anaphase onset until all the chromosomes have successfully attached to th...
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