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Involvement of CENP-F in histone methylation.

Du(Juan),Li(Yan),Zhu(Xueliang) Acta Biochim Biophys Sin (Sha… 2010-06-09

CENP-F (also named mitosin) is a multifunctional protein of 350 kDa. In interphase, it is a nuclear protein, whereas in ...

Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-…

Hewitt(Laura),Tighe(Anthony),Santaguida(Stef… J Cell Biol 2010-07-30

Mps1 is an essential component of the spindle assembly checkpoint. In this study, we describe a novel Mps1 inhibitor, AZ...

The immunodominant epitope of centromere-associated protein A displays homology…

Perosa(Federico),Vicenti(Chiara),Racanelli(V… Clin Immunol 2010-12-07

Some patients with systemic sclerosis express autoantibodies to centromere-associated protein A (CENP-A), but the exact ...

Dual recognition of CENP-A nucleosomes is required for centromere assembly.

Carroll(Christopher W),Milks(Kirstin J),Stra… J Cell Biol 2010-08-12

...CENPs examined, including CENP-K, CENP-H, CENP-I, and CENP-T, and led to a partial reduction in centromeric CENP-A. We p...

Centromere activity in dicentric small supernumerary marker chromosomes.

Ewers(Elisabeth),Yoda(Kinya),Hamid(Ahmed B),… Chromosome Res 2010-10-18

Twenty-five dicentric small supernumerary marker chromosomes (sSMC) derived from #13/21, #14, #15, #18, and #22 were stu...

Centromere identity: a challenge to be faced.

Mehta(Gunjan D),Agarwal(Meenakshi P),Ghosh(S… Mol Genet Genomics 2010-08-06

The centromere is a genetic locus, required for faithful chromosome segregation, where spindle fibers attach to the chro...

Vertebrate kinetochore protein architecture: protein copy number.

Johnston(Katherine),Joglekar(Ajit),Hori(Tets… J Cell Biol 2010-07-08

To define the molecular architecture of the kinetochore in vertebrate cells, we measured the copy number of eight kineto...

A super-resolution map of the vertebrate kinetochore.

Ribeiro(Susana Abreu),Vagnarelli(Paola),Dong… Proc Natl Acad Sci U S A 2010-07-19

A longstanding question in centromere biology has been the organization of CENP-A-containing chromatin and its implicati...

An E3 ubiquitin ligase prevents ectopic localization of the centromeric histone…

Ranjitkar(Prerana),Press(Maximilian O),Yi(Xi… Mol Cell 2010-12-15

Proper centromere function is critical to maintain genomic stability and to prevent aneuploidy, a hallmark of tumors and...

RSK2 is a kinetochore-associated protein that participates in the spindle assem…

Vigneron(S),Brioudes(E),Burgess(A),Labbé(J-C… Oncogene 2010-07-01

The spindle assembly checkpoint (SAC) prevents anaphase onset until all the chromosomes have successfully attached to th...

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