The centromere protein A (CENP-A), a histone H3-like protein, provides an essential role for chromosomal segregation dur...
Faithful chromosome segregation requires the combined activities of the microtubule-based mitotic spindle and the multip...
Centromeres are critically important for chromosome stability and integrity. Most eukaryotes have regional centromeres t...
The vertebrate kinetochore complex assembles at the centromere on alpha-satellite DNA. In humans, alpha-satellite DNA ha...
The kinetochore, which consists of DNA sequence elements and structural proteins, is essential for high-fidelity chromos...
The histone H3 variant centromere protein A (CENP-A) is central to centromere formation throughout eukaryotes. A long-st...
Lung cancer is 1 of the leading causes of cancer death worldwide, and the high mortality from this disease is caused mai...
The organization of the type I interferon (IFN) gene cluster (9p21.3) was studied in a human osteosarcoma cell line (MG6...
To identify in patients with Raynaud's phenomenon (RP) independent markers that predict progression to definite systemic...
Epigenetic histone (H3) modification patterns and the nuclear radial arrangement of select genetic elements were compare...
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