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TP53 BRCA1 CRISPR single-cell cancer

Nagaki(Kiyotaka),Kashihara(Kazunari),Murata(… Chromosome Res 2009-12-24

Centromeres play an important role in chromosome transmission in eukaryotes and comprise specific DNA and proteins that ...

Kalitsis(Paul),Choo(K H Andy) Dev Cell 2009-09-30

The conserved centromere protein C (CENP-C) is indispensable for kinetochore function. Yet its mechanism of action has r...

Tanaka(Koichi),Chang(Hui Li),Kagami(Ayano),W… Dev Cell 2009-09-30

The conserved kinetochore protein CENP-C plays a fundamental role in chromosome segregation, but its specific functions ...

Rosenfeld(Steven S),van Duffelen(Marilyn),Be… J Biol Chem 2009-12-14

We have previously shown that the mitotic motor centrosome protein E (CENP-E) is capable of walking for more than 250 st...

Parra(María Teresa),Gómez(Rocío),Viera(Alber… PLoS Genet 2009-06-15

The assembly of the mitotic centromere has been extensively studied in recent years, revealing the sequence and regulati...

Schittenhelm(Ralf B),Chaleckis(Romanas),Lehn… EMBO J 2009-09-16

The kinetochore is assembled during mitotic and meiotic divisions within the centromeric region of chromosomes. It is co...

Silva(Mariana C C),Jansen(Lars E T) Chromosoma 2009-10-16

Centromeres, the chromosomal loci that form the sites of attachment for spindle microtubules during mitosis, are identif...

Sekulic(Nikolina),Black(Ben E) Nat Cell Biol 2009-07-20

For nucleosome-encoded epigenetic information to be transmitted, an epigenetic mark requires a 'reader' for its physical...

Zeitlin(Samantha G),Baker(Norman M),Chapados… Proc Natl Acad Sci U S A 2009-11-13

The histone H3 variant CENP-A is required for epigenetic specification of centromere identity through a loading mechanis...

Marshall(Owen J),Marshall(Alan T),Choo(K H A… J Cell Biol 2009-02-06

The histone H3 variant centromere protein A (CENP-A) is central to centromere formation throughout eukaryotes. A long-st...

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