We previously identified cancer-upregulated gene 2 (CUG2) as a commonly up-regulated gene in various human cancer tissue...
Faithful chromatin segregation is mediated and controlled by the kinetochore protein network which assembles at centrome...
The centromere serves as the control locus for chromosome segregation at mitosis and meiosis. In most eukaryotes, includ...
Non-coding RNAs are emerging as key players in many fundamental biological processes, including specification of higher-...
We studied the expression levels of cyclins B1, D1, and E1 and the implications of cyclin overexpression for patient out...
DNA methylation is an epigenetically imposed mark of transcriptional repression that is essential for maintenance of chr...
The vertebrate kinetochore complex assembles at the centromere on alpha-satellite DNA. In humans, alpha-satellite DNA ha...
Centromeres are composed of inner kinetochore proteins, which are largely conserved across species, and repetitive DNA, ...
Conserved chromosomal HP1 proteins capable of binding to histone H3 methylated at lysine 9 are believed to provide a dyn...
Faithful chromosome segregation requires the combined activities of the microtubule-based mitotic spindle and the multip...
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