...CENPs. Both CENP-A domains exhibit co-localization of CENP-C and CENP-H, defining a distinct inner kinetochore chromatin...
As a central component of the DNA damage checkpoint pathway, the conserved protein kinase Chk1 mediates cell cycle progr...
Chromosome segregation during mitosis requires the assembly of a large proteinaceous structure termed the kinetochore. I...
In filamentous fungi, hyphal extension depends on the continuous delivery of vesicles to the growing tip. Here, we descr...
Kinetochores are complex protein machines that link chromosomes to spindle microtubules and contain a structural core co...
We report on a small-cell lung cancer case that was heralded by the presence of CENP-B specific anti-centromere autoanti...
The centromere is a chromatin region that serves as the spindle attachment point and directs accurate inheritance of euk...
CENP-A is a centromere-specific histone H3 variant that is essential for kinetochore formation. Here, we report that the...
Here, we report genetic interactions with mdf-1(gk2)/MAD1 in Caenorhabditis elegans. Nine are evolutionarily conserved o...
The back-to-back geometry of sister kinetochores is essential in preventing loss or damage of chromosomes during mitosis...
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