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Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromat…

Alonso(Alicia),Fritz(Björn),Hasson(Dan),Abru… Genome Biol 2008-02-29

...CENPs. Both CENP-A domains exhibit co-localization of CENP-C and CENP-H, defining a distinct inner kinetochore chromatin...

Msc1 acts through histone H2A.Z to promote chromosome stability in Schizosaccha…

Ahmed(Shakil),Dul(Barbara),Qiu(Xinxing),Walw… Genetics 2008-02-11

As a central component of the DNA damage checkpoint pathway, the conserved protein kinase Chk1 mediates cell cycle progr...

KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in ver…

Cheeseman(Iain M),Hori(Tetsuya),Fukagawa(Tat… Mol Biol Cell 2008-11-10

Chromosome segregation during mitosis requires the assembly of a large proteinaceous structure termed the kinetochore. I...

Apical sterol-rich membranes are essential for localizing cell end markers that…

Takeshita(Norio),Higashitsuji(Yuhei),Konzack… Mol Biol Cell 2008-11-10

In filamentous fungi, hyphal extension depends on the continuous delivery of vesicles to the growing tip. Here, we descr...

The CENP-A NAC/CAD kinetochore complex controls chromosome congression and spin…

McClelland(Sarah E),Borusu(Satyarebala),Amar… EMBO J 2008-03-07

Kinetochores are complex protein machines that link chromosomes to spindle microtubules and contain a structural core co...

CENP-B specific anti-centromere autoantibodies heralding small-cell lung cancer…

Briasoulis(Evangelos),Kamposioras(Konstantin… Lung Cancer 2008-09-23

We report on a small-cell lung cancer case that was heralded by the presence of CENP-B specific anti-centromere autoanti...

CENP-B controls centromere formation depending on the chromatin context.

Okada(Teruaki),Ohzeki(Jun-ichirou),Nakano(Me… Cell 2008-02-07

The centromere is a chromatin region that serves as the spindle attachment point and directs accurate inheritance of euk...

Biphasic incorporation of centromeric histone CENP-A in fission yeast.

Takayama(Yuko),Sato(Hiroshi),Saitoh(Shigeaki… Mol Biol Cell 2008-11-10

CENP-A is a centromere-specific histone H3 variant that is essential for kinetochore formation. Here, we report that the...

Synthetic lethal interactions identify phenotypic "interologs" of the spindle a…

Tarailo(Maja),Tarailo(Sanja),Rose(Ann M) Genetics 2008-03-06

Here, we report genetic interactions with mdf-1(gk2)/MAD1 in Caenorhabditis elegans. Nine are evolutionarily conserved o...

cin-4, a gene with homology to topoisomerase II, is required for centromere res…

Stanvitch(Gerald),Moore(Landon L) Genetics 2008-03-27

The back-to-back geometry of sister kinetochores is essential in preventing loss or damage of chromosomes during mitosis...

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