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Anti-centromere antibody positivity: a spectrum of clinical diagnoses and imm...

Li(Y),Xiao(G),Dou(R),Liu(H),Ding(J),Zheng(... Clin Rheumatol 2026-08-19

Anti-centromere antibody (ACA) positivity is recognized in diverse autoimmune diseases beyond systemic sclerosis (SSc). ...

Dual Roads of CENP-A for Centromere Identification.

Hori(T),Fukagawa(T) Bioessays 2026-08-00

Faithful chromosome segregation requires the kinetochore, a macromolecular protein complex that assembles on centromeric...

Immune-related gene signature for predicting biochemical recurrence after RP ...

Lin(Y),Zhou(J) Discov Oncol 2026-07-23

The prognostic role of molecular subtypes of prostate cancer (PCa) patients is still unclear. And we speculated whether ...

Mammalian metaphase kinetochores are elastic and require condensin for robust...

Tran(VM),Tao(J),Rux(CJ),Gomez Siu(D),Rosas... J Cell Biol 2026-10-05

The mammalian kinetochore connects chromosomes to dynamic spindle microtubules. To remain attached, it must maintain str...

The CENtral Identity Crisis: Maintaining Centromere Identity in the Male Germ...

Ní Nualláin(A),O'Gorman(BD),Dunleavy(EM) Annu Rev Genet 2026-08-25

Centromeres are chromosomal loci required for accurate chromosome segregation in cell division and are defined epigeneti...

BUB1B Mitotic Kinase Dependency Reveals CENP-E Inhibition as a Tractable Appr...

Martinez(MJ),Blanco(C),Peinetti(N),Cooke(M... Cancer Res 2026-09-18

Castration-resistant prostate cancer (CRPC) progression despite treatment with potent androgen receptor (AR) antagonists...

Dual pathways via CENP-C and Mis18C recruit HJURP for CENP-A deposition into ...

Hori(T),Mahana(Y),Ariyoshi(M),Fukagawa(T) EMBO J 2026-02-00

Centromere position is specified and maintained by sequence-independent epigenetic mechanisms in vertebrate cells, with ...

Linker histone H1.5 contributes to centromere integrity.

Saha(A),Bui(M),Melters(DP),Arunkumar(G),Ba... Nucleic Acids Res 2026-01-05

Mammalian H1 linker histones comprise a group of 11 non-allelic variants, which have key roles in modulating chromatin. ...

Linking kinetochore attachment to checkpoint control: the role of Aurora B in...

Choi(SY),Park(H),Kim(SS),Kim(H),Park(S),Le... Nucleic Acids Res 2026-01-14

We report that Aurora B kinase-mediated phosphorylation is essential for BubR1 acetylation at lysine 250 (K250), a modif...

A Cross-Tissue Transcriptome-Wide Association Study Reveals Novel Susceptibil...

Zhou(Y),Guo(J) FASEB J 2026-01-31

Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is an autoimmune disease w...

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