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Conservation of functional asymmetry in the mammalian MutLα ATPase.

Johnson(Jennifer R),Erdeniz(Naz),Nguyen(Mega… DNA Repair (Amst) 2011-03-17

...Pms1 ATPase domains to MMR that was not reflected in the biochemical studies. We investigated the effect of mutating the...

Hemizygous deletion of COL3A1, COL5A2, and MSTN causes a complex phenotype with…

Meienberg(Janine),Rohrbach(Marianne),Neuensc… Eur J Hum Genet 2011-02-28

...PMS1, MSTN, C2orf88, HIBCH, INPP1, MFSD6, TMEM194B, NAB1, GLS, STAT1, and STAT4), mutations in three of which (COL5A2, S...

PMS1 from Arabidopsis thaliana: optimization of protein overexpression in Esche…

Galles(Celina),Gomez(Rodrigo L),Spampinato(C… Mol Biol Rep 2011-05-26

...PMS1 was inserted into pET28a downstream a hexa-histidyl leader sequence. The pET28a-AtPMS1 plasmid was efficiently expr...

Single-molecule analysis reveals the kinetics and physiological relevance of Mu…

Park(Jonghyun),Jeon(Yongmoon),In(Daekil),Fis… PLoS One 2011-04-27

...Pms1 have suggested an integral role for a single-stranded DNA (ssDNA) binding activity during MMR. We have developed si...

Three novel germline mutations in MLH1 and MSH2 in families with Lynch syndrome…

Kim(Young Mee),Choe(Chang Gyu),Cho(Somi Kim)… BMB Rep 2011-02-02

...PMS1, and PMS2. We genotyped the MLH1 and MSH2 genes in patients suffering from Lynch syndrome and in 11 unrelated patie...

Modeling of the DNA-binding site of yeast Pms1 by mass spectrometry.

Schorzman(Allison N),Perera(Lalith),Cutalo-P… DNA Repair (Amst) 2011-08-11

...Pms1. The two proteins dimerize along their C-terminal domains (CTDs), and the CTD of Pms1 houses a latent endonuclease ...

Impact of 226C>T MSH2 gene mutation on cancer phenotypes in two HNPCC-associate…

Marafie(Makia J),Al-Awadi(Sadiqa),Al-Mosawi(… Fam Cancer 2010-01-08

...PMS1, and PMS2) are responsible for this disorder. Identifying an affected individual depends on the tumour histopatholo...

Association of common variants in mismatch repair genes and breast cancer susce…

Conde(João),Silva(Susana N),Azevedo(Ana P),T… BMC Cancer 2010-01-13

...PMS1 and MUTYH).,Using unconditional logistic regression we found that MLH3 (L844P, G>A) polymorphism GA (Leu/Pro) and A...

Functional residues on the surface of the N-terminal domain of yeast Pms1.

Arana(Mercedes E),Holmes(Shannon F),Fortune(… DNA Repair (Amst) 2010-06-29

...Pms1 (yPms1) NTD. The structure is similar to the homologous NTDs of Escherichia coli MutL and human PMS2, including the...

Interaction between the Msh2 and Msh6 nucleotide-binding sites in the Saccharom…

Hargreaves(Victoria V),Shell(Scarlet S),Mazu… J Biol Chem 2010-04-12

...Pms1 ternary complexes. Here, we have studied eight mutant Msh2-Msh6 complexes with defective responses to nucleotide bi...

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