Literature Search

Ka(NL),Lim(GY),Kim(SS),Lee(MO) Biomol Ther (Seoul) 2025-11-01

...RAD50-NBS1 complex and disrupted the interaction between NBS1 and ataxia telangiectasia mutated (ATM), a critical step f...

Houmel(M),Pellaton(N),Anchimiuk(A),Gruber(S) EMBO J 2025-11-00

...Rad50 (MR, SbcCD in E. coli) specifically targets DNA termini, yet how hairpin telomeres evade host nuclease degradation...

Chen(Y),Chen(Z),Wang(H),Cui(Z),Li(KL),Song(Z… Science 2025-10-09

...RAD50 to facilitate RAD50 recruitment to damage sites, thereby potentiating homologous recombination repair. Moreover, t...

Ammous-Boukhris(N),Abdelmaksoud-Dammak(R),Be… BMC Cancer 2025-10-09

...RAD50, and BRIP1. Interestingly, four recurrent BRCA1 PVs were observed, one of them is novel. Germline BRCA1/2 PVs were...

Ye(S),Xu(W),Chen(Z),Zhu(C),Ge(Q),Lu(J),Chang… Mol Cancer 2025-10-21

...RAD50, thereby destabilizing the MRE11-RAD50-NBS1 (MRN) complex. Furthermore, ACOX2 activates the cGAS-STING pathway, co...

Gatei(Magtouf),Kijas(Amanda W),Biard(Denis),… Hum Mol Genet 2016-03-22

The MRE11/RAD50/NBN (MRN) complex plays a key role in detecting DNA double-strand breaks, recruiting and activating atax...

Al-Ahmadie(Hikmat),Iyer(Gopa),Hohl(Marcel),A… Cancer Discov 2016-06-02

...RAD50 that attenuated ATM signaling which in the context of CHK1 inhibition contributed, via synthetic lethality, to ext...

Simoneau(Antoine),Robellet(Xavier),Ladouceur… Cell Cycle 2016-05-09

...Rad50-Xrs2 (MRX) complex, is regulated by cell cycle-dependent phosphorylation specifically in mitosis. This modificatio...

Paingankar(Mandar S),Arankalle(Vidya A) Virus Res 2016-05-25

...RAD50 and TLE-4 interacted with HEV 5'UTR. RNA immuno-precipitation studies further confirmed the interaction of DHX9, D...

Aloraifi(Fatima),McDevitt(Trudi),Martiniano(… FEBS J 2016-02-25

...RAD50 (~ 3%), CHEK2 (~ 2%), TP53 (~ 1%), PALB2 (~ 1%), and MRE11A (~ 1%). However, we also identified novel pathogenic v...