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A comparison of the frequency of antibodies to cyclic citrullinated peptides us…

Santiago(Mittermayer),Baron(Murray),Miyachi(… Clin Rheumatol 2008-02-05

The objective was to investigate the frequency of anti-cyclic citrullinated peptides (CCP) antibodies in systemic sclero...

Evolutionary and clinical neocentromeres: two faces of the same coin?

Capozzi(Oronzo),Purgato(Stefania),Verdun di … Chromosoma 2008-10-27

It has been hypothesized that human clinical neocentromeres and evolutionary novel centromeres (ENC) represent two faces...

Defective cohesin is associated with age-dependent misaligned chromosomes in oo…

Liu(Lin),Keefe(David L) Reprod Biomed Online 2008-03-05

Aneuploidy often results from chromosome misalignment at metaphases. Oocytes from senescence-accelerated mice (SAM) exhi...

Epigenetic regulation of centromeric chromatin: old dogs, new tricks?

Allshire(Robin C),Karpen(Gary H) Nat Rev Genet 2008-12-17

The assembly of just a single kinetochore at the centromere of each sister chromatid is essential for accurate chromosom...

CCAN makes multiple contacts with centromeric DNA to provide distinct pathways …

Hori(Tetsuya),Amano(Miho),Suzuki(Aussie),Bac… Cell 2008-12-29

Kinetochore specification and assembly requires the targeted deposition of specialized nucleosomes containing the histon...

The marine natural product adociasulfate-2 as a tool to identify the MT-binding…

Brier(Sébastien),Carletti(Eugénie),DeBonis(S… Biochemistry 2008-01-11

Kinesins are molecular motors that transport cargo along microtubules (MTs). To move forward the motor must attach to th...

Genome-wide analysis reveals a cell cycle-dependent mechanism controlling centr…

Erhardt(Sylvia),Mellone(Barbara G),Betts(Cra… J Cell Biol 2008-12-29

Centromeres are the structural and functional foundation for kinetochore formation, spindle attachment, and chromosome s...

Rapid effects of acute anoxia on spindle kinetochore interactions activate the …

Pandey(Rahul),Heeger(Sebastian),Lehner(Chris… J Cell Sci 2007-11-27

The dramatic chromosome instability in certain tumors might reflect a synergy of spindle checkpoint defects with hypoxic...

Plasticity of fission yeast CENP-A chromatin driven by relative levels of histo…

Castillo(Araceli G),Mellone(Barbara G),Partr… PLoS Genet 2007-08-30

The histone H3 variant CENP-A assembles into chromatin exclusively at centromeres. The process of CENP-A chromatin assem...

Functional genomics identifies a Myb domain-containing protein family required …

Maddox(Paul S),Hyndman(Francie),Monen(Joost)… J Cell Biol 2007-05-03

Nucleosomes containing the centromere-specific histone H3 variant centromere protein A (CENP-A) create the chromatin fou...

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