In yeast and animals, Nuclear Division Cycle 80 (NDC80) is an important kinetochore protein that binds to microtubules a...
The dramatic chromosome instability in certain tumors might reflect a synergy of spindle checkpoint defects with hypoxic...
The fission yeast multiprotein-component Sim4 complex plays a fundamental role in the assembly of a functional kinetocho...
The attachment of spindle microtubules to kinetochores is crucial for accurate segregation of chromosomes to daughter ce...
The assembly of the centromere, a specialized region of DNA along with a constitutive protein complex which resides at t...
Abp1, and the closely related Cbh1 and Cbh2 are homologous to the human centromere-binding protein CENP-B that has been ...
The ICP0 protein of herpes simplex virus type 1 (HSV-1) is a nuclear protein that possesses a well-characterized E3 ubiq...
A small supernumerary marker chromosome (SMC) was observed in a girl with severe developmental delay. Her dysmorphism in...
The centromere is the chromosomal site that joins to microtubules during mitosis for proper segregation. Determining the...
An abnormal chromosome number, aneuploidy, is a common characteristic of tumor cells. Boveri proposed nearly 100 years a...
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