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Assessing pathogenicity of MLH1 variants by co-expression of human MLH1 and PMS…

Vogelsang(Matjaz),Comino(Aleksandra),Zupanec… BMC Cancer 2010-01-13

...PMS1 genes, whose protein products form the MutLalpha complex, were replaced by human orthologs directly on yeast chromo...

A conserved MutS homolog connector domain interface interacts with MutL homolog…

Mendillo(Marc L),Hargreaves(Victoria V),Jami… Proc Natl Acad Sci U S A 2010-02-17

...Pms1 ternary complex. These data indicate that the connector domain of MutS and Msh2 contains the interface for binding ...

[How can we diagnose and better understand inflammatory myopathies? The usefuln…

Sibilia(Jean),Chatelus(Emmanuel),Meyer(Alain… Presse Med 2010-11-02

...PMS1, PMS2) and related antibodies (MLH1, DNA PKcs…), anti-56 kDa, anti-MJ (NXP-2), anti-SAE and anti-p155/p140 (TIF-1γ)...

Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a …

Gorman(Jason),Plys(Aaron J),Visnapuu(Mari-Li… Nat Struct Mol Biol 2010-09-01

...Pms1 diffuses in 1D along DNA via a hopping/stepping mechanism and readily bypasses nucleosomes. This is the first exper...

Clinical impact of HLA-DR15, a minor population of paroxysmal nocturnal haemogl…

Yoshida(Nao),Yagasaki(Hiroshi),Takahashi(Yos… Br J Haematol 2009-05-19

...PMS1) in 103 children with AA enrolled in a multicentre study. In contrast to adults, children with AA did not show an i...

A genome-wide association study of hypertension and blood pressure in African A…

Adeyemo(Adebowale),Gerry(Norman),Chen(Guanji… PLoS Genet 2009-10-27

...PMS1, SLC24A4, YWHA7, IPO7, and CACANA1H. Two of these genes, SLC24A4 (a sodium/potassium/calcium exchanger) and CACNA1H...

Exploring protein phosphorylation in response to DNA damage using differentiall…

Suter(Bernhard),Graham(Christopher),Stagljar… Biotechniques 2009-01-06

...Pms1 as a novel target for phosphorylation in the response to DNA damage and replication fork arrest. Genetic analysis r...

Characterization of a highly conserved binding site of Mlh1 required for exonuc…

Dherin(Claudine),Gueneau(Emeric),Francin(Mat… Mol Cell Biol 2009-02-04

...Pms1 heterodimerization site S1. We show that site S2 is also involved in the interaction between human MLH1 and EXO1 or...

Recognition of O6MeG lesions by MGMT and mismatch repair proficiency may be a p…

Martin(Lynn),Marples(Brian),Coffey(Mary),Law… Radiat Res 2009-11-05

...PMS1, PMS2) and MGMT protein expression signatures were determined in a panel of normal (PWR1E, RWPE1) and malignant (22...

Common germline variation in mismatch repair genes and survival after a diagnos…

Koessler(Thibaud),Azzato(Elizabeth M),Perkin… Int J Cancer 2009-03-19

...PMS1 and PMS2), using a single nucleotide polymorphism (SNP) tagging approach. Genotypes at the tag SNPs and multi-SNP h...

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