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Transcript-RNA-templated DNA recombination and repair.

Keskin(Havva),Shen(Ying),Huang(Fei),Patel(... Nature 2015-01-13

...Rad52-driven homologous recombination during DSB repair. We demonstrate that yeast and human Rad52 proteins efficiently ...

Downregulation of BRCA1 protein in BCR-ABL1 leukemia cells depends on stress-...

Podszywalow-Bartnicka(Paulina),Wolczyk(Mag... Cell Cycle 2015-09-10

...RAD52 to induce synthetic lethality in "BRCAness" CML and BCR-ABL1 -positive ALL cells.

Genetic interactions among homologous recombination mutants in Candida albicans.

Bellido(Alberto),Andaluz(Encarnación),Góme... Fungal Genet Biol 2015-07-01

...rad52-ΔΔ rad59-ΔΔ compared to rad52-ΔΔ. Slow growth and decreased plating efficiency were caused, at least in part, by a...

A RAD52 genetic variant located in a miRNA binding site is associated with gl...

Lu(Chao),Chen(Yi-Dong),Han(Sichong),Wei(Ji... J Neurooncol 2015-12-01

...RAD52 single nucleotide polymorphisms (SNPs) have been identified previously, little was known on how the RAD52 SNPs are...

Tissue inhibitor of metalloproteinases-1 induces a pro-tumourigenic increase ...

Cui(H),Seubert(B),Stahl(E),Dietz(H),Reunin... Oncogene 2015-09-29

...RAD52 and SDHD, were decreased in the presence of TIMP-1. Upon the overexpression of TIMP-1 in tumour cells, miR-210 was...

Both the charged linker region and ATPase domain of Hsp90 are essential for R...

Suhane(Tanvi),Laskar(Shyamasree),Advani(Si... Eukaryot Cell 2015-07-23

...Rad52 without any notable change in the levels of RAD51 or RAD52 transcripts. Our results establish Rad51 as a client of...

Rad51 and Rad52 are involved in homologous recombination of replicating herpe...

Tang(Ka-Wei),Norberg(Peter),Holmudden(Mart... PLoS One 2015-08-18

...Rad52 recombinases in viral recombination was examined in human fibroblast cells 1BR.3.N (wild type) and in GM16097 with...

Rad59-facilitated acquisition of Y' elements by short telomeres delays the on...

Churikov(Dmitri),Charifi(Ferose),Simon(Mar... PLoS Genet 2015-11-10

Telomerase-negative yeasts survive via one of the two Rad52-dependent recombination pathways, which have distinct geneti...

Screening of efficient siRNA target sites directed against gatekeeper genes f...

Ren(Jinghua),Lin(Jusheng),Dong(Xuyang),Xu(... J Huazhong Univ Sci Technol... 2014-01-23

...Rad52, Ku70, Ku80) and screen the more effective target sites from candidates for further research, by using siRNA desig...

Remodeling of the Rad51 DNA strand-exchange protein by the Srs2 helicase.

Sasanuma(Hiroyuki),Furihata(Yuko),Shinohar... Genetics 2014-02-20

...Rad52 (a Rad51 mediator), or replication protein A (RPA; a single-stranded DNA-binding protein). Rather, RPA replaces Ra...

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