The centromere/kinetochore complex plays an essential role in cell and organismal viability by ensuring chromosome movem...
The centromere is a chromatin structure essential for correct segregation of sister chromatids, and defects in this regi...
In recent years, the chromatin field has witnessed a renewed interest in histone variants as pertaining to their structu...
Mitosin/CENP-F is a large nuclear/kinetochore protein containing multiple leucine zipper motifs potentially for protein ...
...CENPs (p = 0.004). Seven of 10 (70%) CENP positive patients with pSS recognised CENP-C alone, compared with one of 18 (6...
Human centromeres are specialized chromatin domains containing the centromeric histone H3 variant CENP-A. CENP-A nucleos...
The Hsp90 inhibitor 17-allylaminogeldanamycin (17-AAG), which is currently in clinical trials, is thought to exert antit...
We report the interactions amongst 20 proteins that specify their assembly to the centromere-kinetochore complex in huma...
A novel cytoplasmic compartment referred to as GW bodies was initially identified using human autoantibodies to a 182 kD...
The mouse jerky gene and its human orthologue, JRK/JH8, encode a putative DNA-binding protein with homology to the CENP-...
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