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Drosophila CENP-A mutations cause a BubR1-dependent early mitotic delay without…

Blower(Michael D),Daigle(Tanya),Kaufman(Thom… PLoS Genet 2006-08-18

The centromere/kinetochore complex plays an essential role in cell and organismal viability by ensuring chromosome movem...

Comprehensive analysis of the ICEN (Interphase Centromere Complex) components e…

Izuta(Hiroshi),Ikeno(Masashi),Suzuki(Nobutak… Genes Cells 2006-09-11

The centromere is a chromatin structure essential for correct segregation of sister chromatids, and defects in this regi...

Histone variants--the structure behind the function.

Ausió(Juan) Brief Funct Genomic Proteomic 2006-12-11

In recent years, the chromatin field has witnessed a renewed interest in histone variants as pertaining to their structu...

Mitosin/CENP-F in mitosis, transcriptional control, and differentiation.

Ma(Li),Zhao(Xiangshan),Zhu(Xueliang) J Biomed Sci 2006-07-31

Mitosin/CENP-F is a large nuclear/kinetochore protein containing multiple leucine zipper motifs potentially for protein ...

Distinct recognition of antibodies to centromere proteins in primary Sjogren's …

Gelber(A C),Pillemer(S R),Baum(B J),Wigley(F… Ann Rheum Dis 2006-08-16

...CENPs (p = 0.004). Seven of 10 (70%) CENP positive patients with pSS recognised CENP-C alone, compared with one of 18 (6...

Human centromeric chromatin is a dynamic chromosomal domain that can spread ove…

Lam(Ai Leen),Boivin(Christopher D),Bonney(Ca… Proc Natl Acad Sci U S A 2006-04-25

Human centromeres are specialized chromatin domains containing the centromeric histone H3 variant CENP-A. CENP-A nucleos...

17-AAG, an Hsp90 inhibitor, causes kinetochore defects: a novel mechanism by wh…

Niikura(Y),Ohta(S),Vandenbeldt(K J),Abdulle(… Oncogene 2006-08-28

The Hsp90 inhibitor 17-allylaminogeldanamycin (17-AAG), which is currently in clinical trials, is thought to exert antit...

Mapping the assembly pathways that specify formation of the trilaminar kinetoch…

Liu(Song-Tao),Rattner(Jerome B),Jablonski(Sa… J Cell Biol 2006-11-28

We report the interactions amongst 20 proteins that specify their assembly to the centromere-kinetochore complex in huma...

GW182 is critical for the stability of GW bodies expressed during the cell cycl…

Yang(Zheng),Jakymiw(Andrew),Wood(Malcolm R),… J Cell Sci 2005-04-11

A novel cytoplasmic compartment referred to as GW bodies was initially identified using human autoantibodies to a 182 kD...

Complex regulation and nuclear localization of JRK protein.

Waldron(R),Moore(T) Biochem Soc Trans 2005-04-18

The mouse jerky gene and its human orthologue, JRK/JH8, encode a putative DNA-binding protein with homology to the CENP-...

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