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Identification of an N-terminal domain of eukaryotic DNA topoisomerase I dispen…

Alsner(J),Svejstrup(J Q),Kjeldsen(E),Sørense… J Biol Chem 1992-08-06

...rad52 top1 Saccharomyces cerevisiae strain. By immunostaining, the 70-amino acid domain is shown to be necessary for nuc...

Identification of a DNA supercoiling activity in Saccharomyces cerevisiae.

Koo(H S),Lau(K),Wu(H Y),Liu(L F) Nucleic Acids Res 1992-11-25

...rad52 mutant cells exhibited the same activity. Partial purification of this activity suggests that a protein factor wit...

Amsacrine and etoposide hypersensitivity of yeast cells overexpressing DNA topo…

Nitiss(J L),Liu(Y X),Harbury(P),Jannatipour(… Cancer Res 1992-09-10

...RAD52+ repair-proficient strains and rad52 mutants that are defective in the repair of double-stranded breaks. These res...

New aspects of the repair and genotoxicity of psoralen photoinduced lesions in …

Averbeck(D),Dardalhon(M),Magaña-Schwencke(N)… J Photochem Photobiol B 1992-12-16

...rad52 dependent pathway is not needed for the repair of 8-MOP induced monoadducts. The results obtained suggest that the...

[A system for analysis of yeast mutants deficient in the genetic recombination …

Korolev(V G),Kozhinov(T N),Kozhin(S A),Peshe… Genetika 1992-12-16

...rad52 mutants were used. The rad52-1 mutation was found sharply decreased the levels both intra- and interplasmid recomb...

Specific complex formation between proteins encoded by the yeast DNA repair and…

Bailly(V),Sommers(C H),Sung(P),Prakash(L),Pr… Proc Natl Acad Sci U S A 1992-10-07

...RAD52. Here, we show that the RAD1 and RAD10 proteins are complexed with each other in vivo. Immunoprecipitation of yeas...

C-terminal truncation of RAP1 results in the deregulation of telomere size, sta…

Kyrion(G),Boakye(K A),Lustig(A J) Mol Cell Biol 1992-11-16

...RAD52 or RAD1 gene product. Third, chromosome loss and nondisjunction rates are elevated 15- to 30-fold above wild-type ...

CTF4 (CHL15) mutants exhibit defective DNA metabolism in the yeast Saccharomyce…

Kouprina(N),Kroll(E),Bannikov(V),Bliskovsky(… Mol Cell Biol 1992-12-29

...rad52 double mutants grew very slowly and produced extremely high levels (50%) of inviable cell division products compar...

Molecular and genetic analysis of the yeast early meiotic recombination genes R…

Cool(M),Malone(R E) Mol Cell Biol 1992-04-13

...rad52 spo13 strain, we isolated several new Rec genes required relatively early in the meiotic recombination process. Th...

Two alternative pathways of double-strand break repair that are kinetically sep…

Fishman-Lobell(J),Rudin(N),Haber(J E) Mol Cell Biol 1992-04-13

...rad52 mutants and in G1-arrested cells.

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