...BRCA1/2 alterations (BRCAa). Cases were additionally stratified according to RB1 mRNA expression level as RB1-high (> 25...
...BRCA1/2, TP53, PTEN, CHEK2, PALB2, and others) was negative, excluding hereditary predisposition. Tumor profiling confir...
...BRCA1, DNMT1, EZH2, PTTG1, SND1, UHRF1). APEX1 was downregulated in CRC, while the other six were upregulated. The diagn...
...BRCA1 mutation who developed MDS following 4 years of maintenance PARPi. Management of therapy-related MDS/AML is variab...
...Brca1-deficient OHCs, whereas, phosphorylation of p53 at S20 is significantly increased in both Brca1-deficient and prof...
...BRCA1/2 mutant breast cancer cell lines MDAMB436 and HCC1428 using a systems-level multi-omics approach, including trans...
...Brca1), c-Fos, activity-regulated cytoskeleton-associated protein (Arc), and Foxg1. We then established a mouse model wi...
Germline loss-of-function mutations in BRCA1 and BRCA2 (BRCA) genes are well-established as causative factors for heredi...
...BRCA1 foci formation. Given the widespread activation of NHEJ throughout the cell cycle, especially in response to radio...
...BRCA1 and BRCA2 expression. Combining Naringenin with other bioactive compounds, chemotherapy drugs, and nanoformulation...
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