...BRCA1 and BRCA2 mutations, was used as a cell model for both in vitro and in vivo studies. Elevated SLX1A expression in ...
...BRCA1, MSH2, PALB2, and STK11. These findings underscore the need for enhanced awareness, improved financial access to t...
...BRCA1/2 emerged as a relevant biomarker in PC, linked to aggressive behavior, unfavorable outcomes and notable responses...
...BRCA1). Mechanistically, UBR5 loss suppressed p38/NF-κB signaling, further compromising DDR and exacerbating chemosensit...
...BRCA1/2, CHEK2, and PALB2 mutations, though familial cancer history suggested a possible hereditary syndrome (FCC suspic...
...BRCA1 inactivation. The study group involved 36 patient samples categorized based on BRCA1 inactivation status. Subseque...
...BRCA1/2 alterations (BRCAa). Cases were additionally stratified according to RB1 mRNA expression level as RB1-high (> 25...
...BRCA1/2 wild-type (BRCA1/2 wt), with mutations observed in 46.15 % (6/13) of BRCA1/2 m versus 72.91 % (183/251) of BRCA1...
This study investigated BRCA1/2 and homologous recombination repair (HR) pathway gene variants in Chinese epithelial ova...
...BRCA1. In conclusion, our findings indicate that the DSB-induced ATM-dependent phosphorylation of DHX9 at S321, which sh...
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