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SERBP1 is required for efficient HR repair and cisplatin chemoresistance in l...

Xie(Y),Chen(Q),Tang(N),Zeng(Y),Zhao(J),Yan... Cell Death Discov 2026-03-19

...BRCA1 mRNA, thus activating HR repair mediated by RAD51. Importantly, BRCA1 knockdown attenuated SERBP1-driven cisplatin...

Cost-effectiveness analysis (CEA) of ovarian cancer preventive strategies for...

Negri(S),Fornari(C),Ye(L),Inzoli(A),Costa(... Eur J Health Econ 2026-03-21

...BRCA1/2 PV carriers. METHODS: The developed Markov decision model simulated the progression of breast cancer and OC in B...

A retrospective analysis of risk-reducing salpingo-oophorectomy performed in ...

Shimizu(Y),Kitai(M),Akada(M),Maeda(M),Yama... Hered Cancer Clin Pract 2026-03-21

...BRCA1 variants were identified in 48 patients (34.5%), BRCA2 variants in 90 (64.7%), and both BRCA1 and BRCA2 variants i...

Analysis of the NLRP3 inflammasome components expression in triple-negative b...

Faria(SS),Costantini(S),Di Gennaro(E),de L... Sci Rep 2026-03-21

Triple-negative breast cancer (TNBC) is an aggressive and immunogenic breast cancer subtype frequently associated with B...

Cancer genomic profiling predicts pathogenicity of BRCA1 and BRCA2 variants.

Kondrashova(O),Johnston(RL),Parsons(MT),Da... medRxiv 2026-03-06

...BRCA1 and 1,639 BRCA2 VUS, we strengthened or enabled classification of 39.48% BRCA1 and 50.52% BRCA2 assessable variant...

Gastric Epithelium from BRCA1 and BRCA2 Carriers Harbors Increased Double-Str...

Buckley(KH),Dungan(ME),Dinh(K),Kelly(GM),H... Mol Cancer Res 2026-07-02

...BRCA1 or BRCA2 have an increased gastric cancer risk. BRCA1 and BRCA2 are tumor suppressor genes involved in promoting h...

Genetic testing for hereditary breast and ovarian cancer in the Murcian popul...

Mestre Terkemani(Y),Rosado Jiménez(L),Garc... Fam Cancer 2026-03-23

...BRCA1 and BRCA2. However, growing evidence indicates that this condition is genetically heterogeneous, and that PV/LPV i...

Clinicopathological Characteristics of Lesions Diagnosed by MRI-Guided Biopsy...

Nagata(A),Tozaki(M),Taruno(K),Nakamura(S),... Eur J Breast Health 2026-03-24

...BRCA1/2 carriers. A total of 130 lesions from 126 patients were reviewed. The BRCA1/2 mutation group had a significantly...

Awareness and attitudes toward BRCA1/2 genetic testing among at-risk women in...

Abdallah(ZA),Khamis(EA),Hendy(A),Abdelalie... Patient Educ Couns 2026-08-00

...BRCA1/2 genetic testing METHODS: A quasi-experimental pre-post study was conducted in the outpatient clinics of the Egyp...

A lasso-based model combining miRNA and clinical variables predicts future ri...

Webber(JW),Wollborn(L),Mishra(S),Alimena(S... Sci Rep 2026-03-24

...BRCA1 and BRCA2. However, most women with HBOC are undiagnosed, and some patients meeting clinical criteria for HBOC wil...

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