...NF1) gene. To evaluate the contribution of Mlh1 MMR deficiency to Nf1 tumorigenesis, Mlh1-/-;Nf1+/- mice were generated....
...NF1) is an autosomal dominant disease caused by loss-of-function mutations in NF1 gene, which encodes a GTPase activatin...
...NF1 tumor neovascularization. Neovascularization in NF1 was studied in Nf+/+(control), Nf1+/-, and Nf1-/-embryos at E-10...
...NF1 allele in the myeloid malignancies of NF1 patients suggests a role of NF1 as a tumor suppressor gene. Loss of 17p wa...
...NF1 gene deletions. In one of the patients with a total NF1 gene deletion, a missense mutation in exon 16 on the other N...
...NF1 factors and parent outcomes. Among parents of youth with NF1, long-term uncertainty of NF1 prognosis may explain why...
...NF1) is a multisystem disorder caused by germline heterozygous NF1 loss-of-function variants. The NF1 gene encodes neuro...
...NF1 gene mutation in a Chinese pedigree of neurofibromatosis type 1 (NF1). Three members of this family were NF1 patient...
...NF1-NS spectrum which were systematically analyzed for mutations in the disease-causing genes NF1 for NF1 and PTPN11 for...
...NF1, genotype/phenotype studies, the RASopathies, NF1 tumorigenesis, mouse NF1 models and potential therapies. What read...
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