Fernández-Rodríguez(Juana),Quiles(Francisco)… BMC Cancer 2012-06-25

...SLX4 gene, which encodes for a scaffold protein involved in the repair of interstrand cross-links, have recently been id...

Vannier(Jean-Baptiste),Pavicic-Kaltenbrunner… Cell 2012-07-02

...SLX4 nuclease complex, resulting in loss of the telomere as a circle. Depleting SLX4 or blocking DNA replication abolish...

Landwehr(Rosa),Bogdanova(Natalia V),Antonenk… Breast Cancer Res Treat 2012-03-22

...SLX4 gene mutations. To investigate whether monoallelic SLX4 gene defects play some role in the inherited component of b...

Holloway(J Kim),Mohan(Swapna),Balmus(Gabriel… PLoS Genet 2011-09-28

The mammalian ortholog of yeast Slx4, BTBD12, is an ATM substrate that functions as a scaffold for various DNA repair ac...

Kang(M H) Clin Genet 2011-09-28

SLX4, a coordinator of structure-specific endo-nucleases, is mutated in a new Fanconi anemia subtype Stoepker et al. (20...

Garner(Elizabeth),Smogorzewska(Agata) FEBS Lett 2011-12-02

...SLX4 exhibit ubiquitin-binding motifs that are important for their DNA repair function, underscoring the importance of u...

Leung(Grace P),Lee(Linda),Schmidt(Thorsten I… J Biol Chem 2011-09-16

...Slx4, Rtt107 interacts with a number of other DNA repair and recombination proteins. These include the evolutionarily co...

Ullal(Pranav),Vilella-Mitjana(Felipe),Jarmuz… PLoS One 2011-09-22

...Slx4 and Rtt101 are not. We demonstrate that Rtt107 has an effect on the efficiency of sister chromatid recombination (S...

Wechsler(Thomas),Newman(Scott),West(Stephen … Nature 2011-05-25

...SLX4 reduces the high frequency of SCEs in Bloom's syndrome cells, indicating that MUS81 and SLX4 promote SCE formation,...

Crossan(Gerry P),van der Weyden(Louise),Rosa… Nat Genet 2011-03-31

...SLX4 protein, a key regulator of nucleases, is critical for DNA damage response. SLX4 nuclease complexes mediate repair ...