Shah Punatar(R),Ho(HN),West(SC) Anal Biochem 2026-07-00

...SLX4-MUS81-EME1-XPF-ERCC1 (SMX complex), or (ii) dissolution mediated by BLM-TopoIIIα-RMI1-RMI2 (BTRR complex). To facil...

Bu(R),Haqawi(W),Razzaq(EAA),Azam(S),Iqbal(K)… Int J Mol Sci 2026-03-14

...SLX4, RAD50, MSH6, POLD1 and NF1. Four patients (36.4%) carried PVs/LPVs in canonical FA pathway genes; this increased t...

Courtes(M),Boissière(T),Barthe(A),Pasero(P),… Nucleic Acids Res 2026-04-13

...Slx4 and Fun30. This local dampening not only promotes cell cycle progression, but also permits Exo1-dependent resection...

Del Re(M),Inglese(E),Bria(E),Blok(EJ),Mathij… Drugs 2026-06-00

...SLX4, impaired lysosomal function, and efflux via ABC transporters. In contrast, resistance to sacituzumab govitecan is ...

Boer(JL),Crippen(SM),Kim(AJ),Kramer(DN),Theu… Nucleic Acids Res 2026-02-24

...SLX4 nuclease scaffold. It was previously found that hairpin-forming CAG/CTG repeats move to the nuclear periphery to ma...

Payliss(BJ),Yun(HY),Doshi(S),Lemak(A),Tse(YW… Nucleic Acids Res 2026-05-05

...SLX4 scaffold. A critical step in SMX assembly is the recruitment of MUS81-EME1 to SLX4 in early mitosis, a process tigh...

Meroni(A),Pellizzari(A),Varisco(N),Leone(F),… EMBO Rep 2026-07-00

...SLX4 and the nucleases MUS81 and XPF to sites of under-replicated DNA. CIP2A loss disrupts this recruitment and leads to...

Zhan(B),Zhong(Y),Chen(X),Dai(Y),Du(L),Lin(Z)… Bioorg Chem 2026-08-18

...SLX4 and MUS81-EME1. Mechanistic studies showed that SCU does not disrupt GEN1-DNA binding but instead binds to the cata...

Malacaria(E),Figlioli(C),Palma(A),Honda(M),V… Nucleic Acids Res 2026-08-10

...SLX4 in S-phase. At deprotected forks, in BRCA2-depleted cells, the CHK2-MUS81 complex assembles downstream of fork reve...

Zhao(XJ),Xu(Y),Zhang(CH),Zhao(C),Liu(L),Wang… Acta Pharmacol Sin 2026-05-00

...SLX4 as an oncogene promoting breast cancer development, potentially by stabilizing mtDNA to suppress pathologic mitocho...