...BRCA1)-associated RING domain 1 (BARD1) in modulating AVA sensitivity. Epigenetic modulation-via global and targeted DNA...
...BRCA1 and BRCA2 genes. Personalized strategies integrating genetic counseling, tailored surveillance and survivorship pr...
...BRCA1/2 testing was 53.4%; 14% of the respondents were variant carriers. Only 16.8% had prior awareness of PGT-M, and 47...
...BRCA1 (0.5%) were most common. The total PGV rate was significantly higher in 2825 self-identified White versus 1527 sel...
...BRCA1 mutant patients, BRCA1 wild-type patients experienced increased T-cell exhaustion and dendritic cell tolerance. We...
...BRCA1/2 mutation carriers have an approved treatment option with the PARP inhibitor (PARPi) olaparib. Characterizing HR-...
Hereditary breast and ovarian cancer (HBOC) syndrome is caused by germline mutations in the BRCA1 and BRCA2 genes, which...
...BRCA1 gene mutation, with preoperative neoadjuvant chemotherapy, no hormone therapy, larger tumor size, negative hormone...
...BRCA1 inactivation. The study group involved 36 patient samples categorized based on BRCA1 inactivation status. Subseque...
...BRCA1, GSN, KRT17, SCD, and SNCG). Kaplan-Meier curves for the TCGA training cohort (P < 0.0001), testing cohort (P = 0....
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