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Radical resection and sentinel lymph node evaluation of mammary-like adenocar...

Markel(L),Rivera(L),Ordobazari(A),Hakam(A)... Gynecol Oncol Rep 2025-10-00

...BRCA1 mutation (variant p.S770, c.2309C>G). Mammary-like gland adenocarcinoma of the vulva is a rare but aggressive neop...

Assessing completeness of cancer family history in EHRs using genetically def...

Kiser(D),Elhanan(G),Schlauch(KA),Read(R),G... Genet Med Open 2025-00-00

...BRCA1 or BRCA2, 34 (41%) met familial risk criteria based on their EHRs; however, an additional 6 (7%) would have met cr...

Circular RNA hsa_Circ_0007552 inhibits lung adenocarcinoma proliferation, mig...

Lin(Y),Li(R),Shen(X),Wu(M),Tang(J),Guo(J),... Front Immunol 2025-00-00

...BRCA1-associated protein 1 (BAP1) mRNA in LUAD tissues and cells were detected by quantitative real-time PCR (qRT-PCR). ...

DNA damage response inhibitors in cancer therapy: Mechanisms, clinical develo...

Lee(SG),Kim(J),Jeong(E),Myung(K) DNA Repair (Amst) 2025-09-00

...BRCA1/2 mutations, present exploitable vulnerabilities for targeted therapies such as PARP inhibitors (PARPi). This revi...

Whole exome sequencing identifies FANCM as a susceptibility gene for estrogen...

Nierenberg(JL),Adamson(AW),Hu(D),Huntsman(... Nat Commun 2025-08-21

...BRCA1, BRCA2, and PALB2 strongly associated with BC. FANCM was previously proposed as a possible susceptibility gene for...

A pilot study of evaluation of a deep-learning-based homologous recombination...

Kwon(GY),Lee(S),Hong(J),Kim(Y),Choi(HJ),Yu... Cancer Genet 2025-11-00

...BRCA1/2 mutations (34.1 %) and 27 with GI-positive (61.4 %). In HGSC, HRD-positive status was associated with solid, pse...

Prediction of Germline BRCA Mutations in High-Risk Breast Cancer Patients Usi...

Park(H),Cho(KR),Lee(S),Cho(D),Park(KH),Cho... Sensors (Basel) 2025-09-04

...BRCA1/2 (BRCA) mutations plays an important role in the treatment planning of high-risk breast cancer patients, but gene...

DNA Damage and Repair in Ovarian Cancer: Focus on MicroRNAs.

Arczewska(KD),Piekiełko-Witkowska(A) Cancers (Basel) 2025-09-15

...BRCA1 targeted by miR-9, miR-1255b, miR-193b, and miR-148b), non-homologous end joining (with RNF8 being regulated by mi...

RAD51 is chromatin enriched and targetable in BRCA1-deficient cells.

Peng(M),Lee(S),Nair(HG),MacGilvary(N),Cong... Mol Cell 2025-09-18

BRCA1 mutant cancers are homologous recombination (HR) deficient, and their sensitivity to anti-cancer therapies such as...

Clinicopathologic features and contralateral breast cancer risk in BRCA1/2 pa...

Taruno(K),Den(H),Takeuchi(M),Inuzuka(M),Ar... Breast Cancer Res Treat 2025-11-00

...BRCA1/2 pathogenic variant carriers, including cases diagnosed after the implementation of national insurance coverage. ...

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