...BRCA1 or BRCA2 mutation face high risks of contralateral breast cancer, and many opt for bilateral mastectomy. We used a...
...Brca1 -related triple negative BC incidence. TT did not influence tumor progression in either model but shaped the Pik3c...
...BRCA1/2, providing additional impetus for identifying inhibitors of this enzyme. We report noncovalent Pol β inhibitors ...
...BRCA1/2 mutation analysis. Of the 157 cases of recurrence, 21 (13%) showed no evidence of disease (NED). NED cases had a...
...BRCA1/2 mutations in melanoma. We conducted an in-depth analysis of risk ratio (RR) in individuals with BRCA1 and BRCA2 ...
BRCA1 mutant cancers are homologous recombination (HR) deficient, and their sensitivity to anti-cancer therapies such as...
...BRCA1-associated protein 1) co-occurs in one-third of patients with TP53-mutated AML, is associated with an erythroid-pr...
...BRCA1 genetic mutation. TNBC is characterized by its very aggressive behavior, elevated rates of recurrence, and restric...
...BRCA1-deficient HGSC with a more elevated HRD score survived significantly longer. Patients with BRCA2-deficient HGSC an...
...BRCA1-deficient tumours preferentially over BRCA1-proficient cells. New synthetic lethal targets are often discovered us...
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