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TP53 BRCA1 CRISPR single-cell cancer

Qu(P),Li(X),Liu(J),Su(X),Han(S),Wang(Y),Lu... ACS Omega 2025-09-23

...BRCA1/2, TP53, MUC1, EGFR, MYC, and others. We further discuss advances in gene editing tools and their combination with...

Zhang(H),Zhou(L),Wang(S),Yao(D),Ma(J),Hu(X... Front Biosci (Landmark Ed) 2025-09-23

...BRCA1, BRCA2, RAD51, RAD51-associated protein 1 (RAD51AP1), and ATM serine/threonine kinase (ATM) promoters. Functionall...

Li(Y),Wang(L),Han(L),Zheng(Z),Yan(J) Front Oncol 2025-00-00

...BRCA1/2, CTNNB1, EPCAM, MLH1, MSH2, MSH6, and PMS2, as well as microsatellite instability (MSI) status in the tumor tiss...

Xue(H),Zhang(C),Lin(D),Gu(Q),Sun(C),Lin(X)... Mater Today Bio 2025-12-00

...BRCA1/2. This study provides an integrated "monitoring-treatment" strategy for diabetic wounds, offering great potential...

Maillard(J),Roumeliotis(TI),Paranjape(E),P... J Proteome Res 2025-10-03

...BRCA1─with different status of BRCA genes grown in 2D and 3D. Using isobaric labeling proteomics, we quantified 6404 pro...

Van Tung(N),Lien(NTK),Huan(LD),Phuong(PC),... Diagnostics (Basel) 2025-08-28

...BRCA1, BRCA2, CASP8, CASR, CHD8, CTNNB1, ESR1, FAN1, FGFR2, HMMR, KLLN, LZTR1, MCPH1, MLH1, MSH2, MSH3, MSH6, NF1, PMS2,...

Park(H),Cho(KR),Lee(S),Cho(D),Park(KH),Cho... Sensors (Basel) 2025-09-04

...BRCA1/2 (BRCA) mutations plays an important role in the treatment planning of high-risk breast cancer patients, but gene...

Kwon(GY),Lee(S),Hong(J),Kim(Y),Choi(HJ),Yu... Cancer Genet 2025-11-00

...BRCA1/2 mutations (34.1 %) and 27 with GI-positive (61.4 %). In HGSC, HRD-positive status was associated with solid, pse...

Wang(Z),Huang(X),Bai(T),Jin(Y),Gong(T),Wu(... Cancer Gene Ther 2025-11-00

...BRCA1/2 or PALB2 due to resistance. Genes associated with cisplatin resistance in patients without BRCA1/2 or PALB2 muta...

Frontera(NM),Ahsan(MD),Chandler(IR),Levi(S... Gynecol Oncol 2025-10-00

...BRCA1/2 PGV was 2.8 (95 % CI 1.5-5.4), with similar ORs for BRCA1 (3.2 [95 % CI 1.6-6.3]) and BRCA2 (2.8 [95 % CI 1.2-6....

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