...BRCA1 targeted by miR-9, miR-1255b, miR-193b, and miR-148b), non-homologous end joining (with RNF8 being regulated by mi...
...BRCA1/2 genes. The BRCA1/2 pathogenetic variants are currently used, in clinical setting, as predictive markers for PARP...
...BRCA1 promoter methylation in homologous recombination-deficient ovarian cancers or MLH1 promoter methylation in deficie...
...BRCA1-encoded protein. To our knowledge, this is the first functional characterization of the variant BRCA1 c.5193 + 2du...
...BRCA1 + or BRCA2+ (mutation carriers) or BRCA1- or BRCA2- (mutation non-carriers). Comparative analyses were conducted t...
...BRCA1-interacting protein C-terminal helicase 1 (BRIP1) mRNA, resulting in a malignant phenotype of ovarian cancer. Over...
Polygenic risk scores (PRS) have been shown to be predictive of breast cancer (BC) risk in European BRCA1 and BRCA2 path...
...BRCA1-Associated RING Domain 1) plays a complex role in tumor biology, functioning either as a tumor suppressor or as an...
...BRCA1 and BRCA2 genes. Personalized strategies integrating genetic counseling, tailored surveillance and survivorship pr...
...BRCA1/2 testing was 53.4%; 14% of the respondents were variant carriers. Only 16.8% had prior awareness of PGT-M, and 47...
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