...BRCA1, CCNE2, CDC25A, CDC25C, CDK2, E2F1, H2AFX, PMAIP1, RAD51, and SMC1A. These findings indicate that γT3 and δT3 inhi...
...BRCA1 in ependymoma, SPIDR in HGG, SMC5 in MB, and SMARCAL1 in osteosarcoma (OS). Importantly, the SMARCAL1:OS associati...
...BRCA1 and BRCA2 remain important, smoking-particularly long-term and heavy use-emerges as a modifiable risk factor that ...
...BRCA1)] expression and inhibiting phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/mTOR signaling; and (4) reduci...
...BRCA1-associated protein 1 (BAP1)-negative tumors, T cell function and tumor necrosis factor (TNF) superfamily genes wer...
...BRCA1 PVs were observed, one of them is novel. Germline BRCA1/2 PVs were significantly more frequent in patients under 5...
...BRCA1, BRCA2, and mismatch repair genes) increase the risk for developing the disease. Due to the lack of effective scre...
...BRCA1-mutated TNBC. Preclinical and clinical trials revealed that the response to PARP inhibition was directly correlate...
...BRCA1/2 deficiencies, therapeutic options remain limited for those without such mutations. Here, we uncover a critical r...
...BRCA1/2 LOH group having the best efficacy (median PFS, undefined), followed by BRCA1 methylation group (median PFS, 23....
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