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TP53 BRCA1 CRISPR single-cell cancer

Chantrill(Lorraine A),Nagrial(Adnan M),Wat... Clin Cancer Res 2016-03-31

...BRCA1, BRCA2, PALB2, ATM).,Tumor biopsy and archived tumor samples were collected from 93 patients and 76 were screened....

Wei(Bin),Han(Qin),Xu(Lijuan),Zhang(Xiaohui... BMC Cancer 2016-03-01

...BRCA1 expression simultaneously (P<0.001); while in patients with high JWA expression, high BRCA1 mRNA expression was co...

Blein(Sophie),Bardel(Claire),Danjean(Vince... Breast Cancer Res 2016-04-18

...BRCA1 and BRCA2 genes have a high lifetime risk of breast cancer. BRCA1 and BRCA2 are involved in DNA double-strand brea...

Zhu(Jinhai),Zhang(Hui),Zhu(Zhengzhi),Zhang... Naunyn Schmiedebergs Arch P... 2016-05-23

...BRCA1 gene expression was inversely related to FAC treatment. Western blot analysis indicated that BCL-2 and FAK protein...

Feng(Xiaolan),Li(Haocheng),Dean(Michelle),... Breast Cancer Res 2016-01-15

...BRCA1/2, thereby orchestrating complex signaling pathways involved in cell cycle arrest, DNA repair, senescence and apop...

Cybulski(Cezary),Lubinski(Jan),Huzarski(To... Breast Cancer Res Treat 2016-02-04

...BRCA1 or BRCA2 mutation. Information regarding baseline daily alcohol consumption was abstracted from a research questio...

Farzin(Mahtab),Toon(Christopher W),Clarkso... Pathology 2016-04-22

BRCA1-associated protein 1 (BAP1) is a tumour suppressor gene frequently inactivated in mesothelioma, rarely also in ass...

Upton(Dannielle H),Fuller(Emily S),Colvin(... Horm Cancer 2016-03-16

...Brca1 disruption, denoted Brca1(GC-/-). Furthermore, ovary-specific Brca1(GC-/-) was combined with global Trp53 haploins...

Li(Dongguo),Xia(Hong),Li(Zhen-ya),Hua(Lin)... Biomed Res Int 2016-02-04

...BRCA1-miR-143-miR-145 pairs was selected for experimental validation. The study results indicated that BRCA1 positively ...

Price(R Jordan),Lillycrop(Karen A),Burdge(... Nutr Res 2016-03-01

...BRCA1 and BRCA2. FA treatment induced dose-related increases in BRCA1 mRNA expression in HepG2, Huh-7D12, Hs578T, and JU...

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