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Gene analysis techniques and susceptibility gene discovery in non-BRCA1/BRCA2...

Aloraifi(Fatima),Boland(Michael R),Green(A... Surg Oncol 2016-02-22

...BRCA1 or BRCA2 genes have up to an 85% risk of developing breast cancer in their lifetimes. These patients are candidate...

Genome-wide association study of susceptibility loci for breast cancer in Sar...

Palomba(Grazia),Loi(Angela),Porcu(Eleonora... BMC Cancer 2016-02-05

...BRCA1/2-mutation-negative breast cancer to 2171 healthy Sardinian blood donors. DNA was genotyped using GeneChip Human M...

Does rapid genetic counseling and testing in newly diagnosed breast cancer pa...

Wevers(Marijke R),Ausems(Margreet G E M),V... Genet Med 2016-10-20

Female breast cancer patients carrying a BRCA1/2 mutation have an increased risk of second primary breast cancer. Rapid ...

XomAnnotate: Analysis of Heterogeneous and Complex Exome- A Step towards Tran...

Talukder(Asoke K),Ravishankar(Shashidhar),... PLoS One 2016-01-19

...BRCA1/BRCA2 breast cancer exome data. The results showed that the most significantly affected pathways across all sample...

Mitochondrial fission determines cisplatin sensitivity in tongue squamous cel...

Fan(Song),Liu(Bodu),Sun(Lijuan),Lv(Xiao-bi... Oncotarget 2016-04-18

...BRCA1 transactivated miR-593-5p expression and attenuated cisplatin sensitivity in vitro. The BRCA1-miR-593-5p-MFF axis ...

Loss of the N-terminal methyltransferase NRMT1 increases sensitivity to DNA d...

Bonsignore(Lindsay A),Butler(Jill Sergeske... Oncotarget 2016-04-05

...BRCA1 and BRCA2, its loss may result in tumors with enhanced sensitivity to diverse DNA damaging chemotherapeutics.

BRCA1 and CtIP Are Both Required to Recruit Dna2 at Double-Strand Breaks in H...

Hoa(Nguyen Ngoc),Kobayashi(Junya),Omura(Ma... PLoS One 2016-01-19

...BRCA1), which physically interacts with CtIP and contributes to DSB resection, also inhibited the recruitment of Dna2. M...

BRCA1-like signature in triple negative breast cancer: Molecular and clinical...

Severson(Tesa M),Peeters(Justine),Majewski... Mol Oncol 2016-08-15

...BRCA1-like or non-BRCA1-like. BRCA1 mutation, promoter methylation, BRCA1-like status and genome-wide expression data wa...

Differential Potential of Pharmacological PARP Inhibitors for Inhibiting Cell...

Węsierska-Gądek(Józefa),Mauritz(Matthias),... J Cell Biochem 2016-08-09

...BRCA1-positive BT-20 cells, but not BRCA1-deficient SKBr-3 cells. These results raised the possibility that other PARP-1...

Phase II neoadjuvant clinical trial of carboplatin and eribulin in women with...

Kaklamani(Virginia G),Jeruss(Jacqueline S)... Breast Cancer Res Treat 2016-02-24

...BRCA1/BRCA2 mutation status)], protein-based biomarkers (Ki67, TP53, androgen receptor, Cyclin E, CDK2, Cyclin D, CDK4, ...

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